Mitochondria in skeletal muscle: adaptable rheostats of apoptotic susceptibility
Apoptosis is an essential process that plays a critical role in both tissue development and maintenance. Apoptosis has been shown to be involved in skeletal muscle atrophy resulting from chronic muscular disuse, sarcopenia, and mitochondrial myopathies. Exercise may attenuate some of the proapoptoti...
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| Veröffentlicht in: | Exercise and sport sciences reviews 2008-07, Vol.36 (3), p.116-121 |
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| container_title | Exercise and sport sciences reviews |
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| creator | Adhihetty, Peter J O'Leary, Michael F N Hood, David A |
| description | Apoptosis is an essential process that plays a critical role in both tissue development and maintenance. Apoptosis has been shown to be involved in skeletal muscle atrophy resulting from chronic muscular disuse, sarcopenia, and mitochondrial myopathies. Exercise may attenuate some of the proapoptotic adaptations that occur during these conditions. This review will focus on the factors influencing mitochondrially mediated apoptosis in skeletal muscle. |
| doi_str_mv | 10.1097/JES.0b013e31817be7b7 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0091-6331 |
| ispartof | Exercise and sport sciences reviews, 2008-07, Vol.36 (3), p.116-121 |
| issn | 0091-6331 1538-3008 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69257056 |
| source | MEDLINE; Journals@Ovid LWW Legacy Archive; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Apoptosis - physiology Humans Mitochondria, Muscle - physiology Muscle, Skeletal - metabolism Muscular Atrophy - pathology |
| title | Mitochondria in skeletal muscle: adaptable rheostats of apoptotic susceptibility |
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