Preferences for colloid use in Scandinavian intensive care units
Background: Fluid resuscitation is a frequent intervention in intensive care. Colloids are widely used, but recent data suggest harm by some of these solutions. This calls for more clinical studies on this matter, but the current preferences for colloid use in Scandinavian intensive care units (ICUs...
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Veröffentlicht in: | Acta anaesthesiologica Scandinavica 2008-07, Vol.52 (6), p.750-758 |
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description | Background: Fluid resuscitation is a frequent intervention in intensive care. Colloids are widely used, but recent data suggest harm by some of these solutions. This calls for more clinical studies on this matter, but the current preferences for colloid use in Scandinavian intensive care units (ICUs) are unknown.
Methods: In March–May 2007, 120 Scandinavian ICUs were invited to answer a web‐based survey consisting of 18 questions on types of colloids, indications, contraindications and rationale of use.
Results: Seventy‐three ICUs, of which 31 were university hospital units, answered the questionnaire. Most ICUs used both synthetic and natural colloids, and hydroxyethyl starch (HES) 130/0.4 was the preferred colloid in 59 units. Eleven ICUs had protocols for colloid use. The most frequent indication was second‐line fluid for hypovolaemia, but one in three ICUs used colloids as first‐line fluid. Thirty‐five ICUs had contraindications, which were mainly for the use of synthetic colloids (acute renal failure 25 units, bleeding 15 units). Most units based the use of colloids on theoretical knowledge and tradition. Sixty‐five and 54 ICUs were ready to change colloid use based on data from randomised trials of ICU patients showing changes in mortality or renal function, respectively.
Conclusion: Most Scandinavian ICUs use both synthetic and natural colloids, but HES 130/0.4 is by far the preferred colloid. Few units have protocols for colloid use, but most use them for hypovolaemia, and the majority have no contraindications. Most ICUs are ready to change colloid use if randomised trials in ICU patients show changes in mortality or renal function. |
doi_str_mv | 10.1111/j.1399-6576.2008.01690.x |
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Methods: In March–May 2007, 120 Scandinavian ICUs were invited to answer a web‐based survey consisting of 18 questions on types of colloids, indications, contraindications and rationale of use.
Results: Seventy‐three ICUs, of which 31 were university hospital units, answered the questionnaire. Most ICUs used both synthetic and natural colloids, and hydroxyethyl starch (HES) 130/0.4 was the preferred colloid in 59 units. Eleven ICUs had protocols for colloid use. The most frequent indication was second‐line fluid for hypovolaemia, but one in three ICUs used colloids as first‐line fluid. Thirty‐five ICUs had contraindications, which were mainly for the use of synthetic colloids (acute renal failure 25 units, bleeding 15 units). Most units based the use of colloids on theoretical knowledge and tradition. Sixty‐five and 54 ICUs were ready to change colloid use based on data from randomised trials of ICU patients showing changes in mortality or renal function, respectively.
Conclusion: Most Scandinavian ICUs use both synthetic and natural colloids, but HES 130/0.4 is by far the preferred colloid. Few units have protocols for colloid use, but most use them for hypovolaemia, and the majority have no contraindications. Most ICUs are ready to change colloid use if randomised trials in ICU patients show changes in mortality or renal function.</description><identifier>ISSN: 0001-5172</identifier><identifier>EISSN: 1399-6576</identifier><identifier>DOI: 10.1111/j.1399-6576.2008.01690.x</identifier><identifier>PMID: 18582303</identifier><identifier>CODEN: AANEAB</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adult ; Anesthesia ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Colloids ; Colloids - therapeutic use ; Contraindications ; fluid therapy ; Fluid Therapy - methods ; Health Care Surveys ; Humans ; Hydroxyethyl Starch Derivatives - therapeutic use ; intensive care ; Intensive Care Units ; Medical sciences ; Plasma Substitutes - therapeutic use ; plasma volume expanders ; Scandinavian and Nordic Countries ; Surveys and Questionnaires</subject><ispartof>Acta anaesthesiologica Scandinavica, 2008-07, Vol.52 (6), p.750-758</ispartof><rights>2008 The Authors. Journal compilation © 2008 The Acta Anaesthesiologica Scandinavica Foundation</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4350-30a5e6a97538fd3f695fd939c064e11e726508fa67bc5205ad5e01ed28955e803</citedby><cites>FETCH-LOGICAL-c4350-30a5e6a97538fd3f695fd939c064e11e726508fa67bc5205ad5e01ed28955e803</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1399-6576.2008.01690.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1399-6576.2008.01690.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20438903$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18582303$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>FLUIDS study investigators for the Scandinavian Critical Care Trials Group</creatorcontrib><creatorcontrib>The FLUIDS study investigators for the Scandinavian Critical Care Trials Group</creatorcontrib><title>Preferences for colloid use in Scandinavian intensive care units</title><title>Acta anaesthesiologica Scandinavica</title><addtitle>Acta Anaesthesiol Scand</addtitle><description>Background: Fluid resuscitation is a frequent intervention in intensive care. Colloids are widely used, but recent data suggest harm by some of these solutions. This calls for more clinical studies on this matter, but the current preferences for colloid use in Scandinavian intensive care units (ICUs) are unknown.
Methods: In March–May 2007, 120 Scandinavian ICUs were invited to answer a web‐based survey consisting of 18 questions on types of colloids, indications, contraindications and rationale of use.
Results: Seventy‐three ICUs, of which 31 were university hospital units, answered the questionnaire. Most ICUs used both synthetic and natural colloids, and hydroxyethyl starch (HES) 130/0.4 was the preferred colloid in 59 units. Eleven ICUs had protocols for colloid use. The most frequent indication was second‐line fluid for hypovolaemia, but one in three ICUs used colloids as first‐line fluid. Thirty‐five ICUs had contraindications, which were mainly for the use of synthetic colloids (acute renal failure 25 units, bleeding 15 units). Most units based the use of colloids on theoretical knowledge and tradition. Sixty‐five and 54 ICUs were ready to change colloid use based on data from randomised trials of ICU patients showing changes in mortality or renal function, respectively.
Conclusion: Most Scandinavian ICUs use both synthetic and natural colloids, but HES 130/0.4 is by far the preferred colloid. Few units have protocols for colloid use, but most use them for hypovolaemia, and the majority have no contraindications. Most ICUs are ready to change colloid use if randomised trials in ICU patients show changes in mortality or renal function.</description><subject>Adult</subject><subject>Anesthesia</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Colloids</subject><subject>Colloids - therapeutic use</subject><subject>Contraindications</subject><subject>fluid therapy</subject><subject>Fluid Therapy - methods</subject><subject>Health Care Surveys</subject><subject>Humans</subject><subject>Hydroxyethyl Starch Derivatives - therapeutic use</subject><subject>intensive care</subject><subject>Intensive Care Units</subject><subject>Medical sciences</subject><subject>Plasma Substitutes - therapeutic use</subject><subject>plasma volume expanders</subject><subject>Scandinavian and Nordic Countries</subject><subject>Surveys and Questionnaires</subject><issn>0001-5172</issn><issn>1399-6576</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkEtP9CAUhonR6Hj5C6Yb3bUeSqGw-BInxls0XqJGdwTpacJ8Haow1fHf2zqTcSsbOOF54ZyHkIRCRvt1NMkoUyoVvBRZDiAzoEJBNl8jo9XFOhkBAE05LfMtsh3jpC9ZodQm2aKSy5wBG5Hju4A1BvQWY1K3IbFt07SuSrqIifPJgzW-ct58OOP7eoY-ug9MrAmYdN7N4i7ZqE0TcW-575Cns9PHk4v0-vb88mR8ndqCcUgZGI7CqJIzWVesForXlWLKgiiQUixzwUHWRpSvlufATcURKFa5VJyjBLZDDhfvvoX2vcM401MXLTaN8dh2UQuVc8FgAOUCtKGNsZ9OvwU3NeFLU9CDPT3RgyQ9SNKDPf1jT8_76P7yj-51itVvcKmrBw6WgInWNHUw3rq44nIomFQ_3L8F9-ka_PpzA3o8fhhOfT5d5F2c4XyVN-G_FiUruX6-Odfl88v91YsstGTfuluY0g</recordid><startdate>200807</startdate><enddate>200807</enddate><creator>FLUIDS study investigators for the Scandinavian Critical Care Trials Group</creator><creator>The FLUIDS study investigators for the Scandinavian Critical Care Trials Group</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200807</creationdate><title>Preferences for colloid use in Scandinavian intensive care units</title></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4350-30a5e6a97538fd3f695fd939c064e11e726508fa67bc5205ad5e01ed28955e803</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Anesthesia</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Colloids</topic><topic>Colloids - therapeutic use</topic><topic>Contraindications</topic><topic>fluid therapy</topic><topic>Fluid Therapy - methods</topic><topic>Health Care Surveys</topic><topic>Humans</topic><topic>Hydroxyethyl Starch Derivatives - therapeutic use</topic><topic>intensive care</topic><topic>Intensive Care Units</topic><topic>Medical sciences</topic><topic>Plasma Substitutes - therapeutic use</topic><topic>plasma volume expanders</topic><topic>Scandinavian and Nordic Countries</topic><topic>Surveys and Questionnaires</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>FLUIDS study investigators for the Scandinavian Critical Care Trials Group</creatorcontrib><creatorcontrib>The FLUIDS study investigators for the Scandinavian Critical Care Trials Group</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta anaesthesiologica Scandinavica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><aucorp>FLUIDS study investigators for the Scandinavian Critical Care Trials Group</aucorp><aucorp>The FLUIDS study investigators for the Scandinavian Critical Care Trials Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preferences for colloid use in Scandinavian intensive care units</atitle><jtitle>Acta anaesthesiologica Scandinavica</jtitle><addtitle>Acta Anaesthesiol Scand</addtitle><date>2008-07</date><risdate>2008</risdate><volume>52</volume><issue>6</issue><spage>750</spage><epage>758</epage><pages>750-758</pages><issn>0001-5172</issn><eissn>1399-6576</eissn><coden>AANEAB</coden><abstract>Background: Fluid resuscitation is a frequent intervention in intensive care. Colloids are widely used, but recent data suggest harm by some of these solutions. This calls for more clinical studies on this matter, but the current preferences for colloid use in Scandinavian intensive care units (ICUs) are unknown.
Methods: In March–May 2007, 120 Scandinavian ICUs were invited to answer a web‐based survey consisting of 18 questions on types of colloids, indications, contraindications and rationale of use.
Results: Seventy‐three ICUs, of which 31 were university hospital units, answered the questionnaire. Most ICUs used both synthetic and natural colloids, and hydroxyethyl starch (HES) 130/0.4 was the preferred colloid in 59 units. Eleven ICUs had protocols for colloid use. The most frequent indication was second‐line fluid for hypovolaemia, but one in three ICUs used colloids as first‐line fluid. Thirty‐five ICUs had contraindications, which were mainly for the use of synthetic colloids (acute renal failure 25 units, bleeding 15 units). Most units based the use of colloids on theoretical knowledge and tradition. Sixty‐five and 54 ICUs were ready to change colloid use based on data from randomised trials of ICU patients showing changes in mortality or renal function, respectively.
Conclusion: Most Scandinavian ICUs use both synthetic and natural colloids, but HES 130/0.4 is by far the preferred colloid. Few units have protocols for colloid use, but most use them for hypovolaemia, and the majority have no contraindications. Most ICUs are ready to change colloid use if randomised trials in ICU patients show changes in mortality or renal function.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>18582303</pmid><doi>10.1111/j.1399-6576.2008.01690.x</doi><tpages>9</tpages></addata></record> |
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subjects | Adult Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Colloids Colloids - therapeutic use Contraindications fluid therapy Fluid Therapy - methods Health Care Surveys Humans Hydroxyethyl Starch Derivatives - therapeutic use intensive care Intensive Care Units Medical sciences Plasma Substitutes - therapeutic use plasma volume expanders Scandinavian and Nordic Countries Surveys and Questionnaires |
title | Preferences for colloid use in Scandinavian intensive care units |
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