Carcinosarcoma of the rectosigmoid colon in a 13‐year‐old girl
Reported herein is an unusual case of carcinosarcoma of the colon. A 13‐year‐old girl was transferred to Chonbuk National University Hospital, Korea with a known pelvic mass. CT and magnetic resonance imaging confirmed a large pelvic mass. A sarcoma was diagnosed following colonoscopic biopsy. An ul...
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Veröffentlicht in: | Pathology international 2008-07, Vol.58 (7), p.445-450 |
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description | Reported herein is an unusual case of carcinosarcoma of the colon. A 13‐year‐old girl was transferred to Chonbuk National University Hospital, Korea with a known pelvic mass. CT and magnetic resonance imaging confirmed a large pelvic mass. A sarcoma was diagnosed following colonoscopic biopsy. An ultra‐low anterior resection with pelvic lymph node dissection was performed. The tumor consisted of a well‐differentiated adenocarcinoma showing strong immunoreactivity to epithelial markers (pancytokeratin, cytokeratin 7, cytokeratin 19, cytokeratin 20, epithelial membrane antigen, and CEA) and a sarcomatous lesion with strong diffuse vimentin expression but no immunoreactivity to any of the six epithelial markers. Carcinosarcomas of the colon are extremely rare, and all reported cases involve adults. To the authors' knowledge, this is the first reported case of a carcinosarcoma of the colon in a child. |
doi_str_mv | 10.1111/j.1440-1827.2008.02252.x |
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A 13‐year‐old girl was transferred to Chonbuk National University Hospital, Korea with a known pelvic mass. CT and magnetic resonance imaging confirmed a large pelvic mass. A sarcoma was diagnosed following colonoscopic biopsy. An ultra‐low anterior resection with pelvic lymph node dissection was performed. The tumor consisted of a well‐differentiated adenocarcinoma showing strong immunoreactivity to epithelial markers (pancytokeratin, cytokeratin 7, cytokeratin 19, cytokeratin 20, epithelial membrane antigen, and CEA) and a sarcomatous lesion with strong diffuse vimentin expression but no immunoreactivity to any of the six epithelial markers. Carcinosarcomas of the colon are extremely rare, and all reported cases involve adults. 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A 13‐year‐old girl was transferred to Chonbuk National University Hospital, Korea with a known pelvic mass. CT and magnetic resonance imaging confirmed a large pelvic mass. A sarcoma was diagnosed following colonoscopic biopsy. An ultra‐low anterior resection with pelvic lymph node dissection was performed. The tumor consisted of a well‐differentiated adenocarcinoma showing strong immunoreactivity to epithelial markers (pancytokeratin, cytokeratin 7, cytokeratin 19, cytokeratin 20, epithelial membrane antigen, and CEA) and a sarcomatous lesion with strong diffuse vimentin expression but no immunoreactivity to any of the six epithelial markers. Carcinosarcomas of the colon are extremely rare, and all reported cases involve adults. To the authors' knowledge, this is the first reported case of a carcinosarcoma of the colon in a child.</description><subject>Adolescent</subject><subject>carcinosarcoma</subject><subject>Carcinosarcoma - metabolism</subject><subject>Carcinosarcoma - pathology</subject><subject>Carcinosarcoma - surgery</subject><subject>child</subject><subject>colon</subject><subject>Colorectal Neoplasms - metabolism</subject><subject>Colorectal Neoplasms - pathology</subject><subject>Colorectal Neoplasms - surgery</subject><subject>Female</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><issn>1320-5463</issn><issn>1440-1827</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkL1OwzAUhS0EolB4BeSJLcH_dgYGqPipVAEDzJbj2CVVUhe7Fe3GI_CMPAkJrWDlLudK95xzpQ8AiFGOu7mY5ZgxlGFFZE4QUjkihJN8vQeOfg_73U4JyjgTdACOU5ohhCUV6BAMsOJSYsyPwPXIRFvPQ-oktAYGD5evDkZnlyHV0zbUFbShCXNYz6GBmH59fG6ciZ2EpoLTOjYn4MCbJrnTnQ7By-3N8-g-mzzejUdXk8wyJUiGrfcFx5UilZS2orhkpGJeMU9LYYUplVfcFIwaZ52SuMBIOK7KwnBnvUV0CM63vYsY3lYuLXVbJ-uaxsxdWCUtCsKUFLgzqq3RxpBSdF4vYt2auNEY6Z6fnukek-4x6Z6f_uGn1130bPdjVbau-gvugHWGy63hvW7c5t_F-mn80G_0G_n4f-c</recordid><startdate>200807</startdate><enddate>200807</enddate><creator>Jeong, Yeon Jun</creator><creator>Lee, Min Ro</creator><creator>Kim, Jae Chun</creator><creator>Hwang, Pyoung Han</creator><creator>Moon, Woo Sung</creator><creator>Chung, Myoung‐Ja</creator><general>Blackwell Publishing Asia</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200807</creationdate><title>Carcinosarcoma of the rectosigmoid colon in a 13‐year‐old girl</title><author>Jeong, Yeon Jun ; Lee, Min Ro ; Kim, Jae Chun ; Hwang, Pyoung Han ; Moon, Woo Sung ; Chung, Myoung‐Ja</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4862-1cff951d82d77cd31b42d4f84f3b6c6ab8f85a943aece8719106e58b9a5ecfc03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adolescent</topic><topic>carcinosarcoma</topic><topic>Carcinosarcoma - metabolism</topic><topic>Carcinosarcoma - pathology</topic><topic>Carcinosarcoma - surgery</topic><topic>child</topic><topic>colon</topic><topic>Colorectal Neoplasms - metabolism</topic><topic>Colorectal Neoplasms - pathology</topic><topic>Colorectal Neoplasms - surgery</topic><topic>Female</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jeong, Yeon Jun</creatorcontrib><creatorcontrib>Lee, Min Ro</creatorcontrib><creatorcontrib>Kim, Jae Chun</creatorcontrib><creatorcontrib>Hwang, Pyoung Han</creatorcontrib><creatorcontrib>Moon, Woo Sung</creatorcontrib><creatorcontrib>Chung, Myoung‐Ja</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pathology international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jeong, Yeon Jun</au><au>Lee, Min Ro</au><au>Kim, Jae Chun</au><au>Hwang, Pyoung Han</au><au>Moon, Woo Sung</au><au>Chung, Myoung‐Ja</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Carcinosarcoma of the rectosigmoid colon in a 13‐year‐old girl</atitle><jtitle>Pathology international</jtitle><addtitle>Pathol Int</addtitle><date>2008-07</date><risdate>2008</risdate><volume>58</volume><issue>7</issue><spage>445</spage><epage>450</epage><pages>445-450</pages><issn>1320-5463</issn><eissn>1440-1827</eissn><abstract>Reported herein is an unusual case of carcinosarcoma of the colon. A 13‐year‐old girl was transferred to Chonbuk National University Hospital, Korea with a known pelvic mass. CT and magnetic resonance imaging confirmed a large pelvic mass. A sarcoma was diagnosed following colonoscopic biopsy. An ultra‐low anterior resection with pelvic lymph node dissection was performed. The tumor consisted of a well‐differentiated adenocarcinoma showing strong immunoreactivity to epithelial markers (pancytokeratin, cytokeratin 7, cytokeratin 19, cytokeratin 20, epithelial membrane antigen, and CEA) and a sarcomatous lesion with strong diffuse vimentin expression but no immunoreactivity to any of the six epithelial markers. Carcinosarcomas of the colon are extremely rare, and all reported cases involve adults. To the authors' knowledge, this is the first reported case of a carcinosarcoma of the colon in a child.</abstract><cop>Melbourne, Australia</cop><pub>Blackwell Publishing Asia</pub><pmid>18577115</pmid><doi>10.1111/j.1440-1827.2008.02252.x</doi><tpages>6</tpages></addata></record> |
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subjects | Adolescent carcinosarcoma Carcinosarcoma - metabolism Carcinosarcoma - pathology Carcinosarcoma - surgery child colon Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Colorectal Neoplasms - surgery Female Humans Immunohistochemistry |
title | Carcinosarcoma of the rectosigmoid colon in a 13‐year‐old girl |
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