Human α Spectrin II and the Fanconi Anemia Proteins FANCA and FANCC Interact to Form a Nuclear Complex

Fanconi anemia (FA) is a genetic disorder characterized by bone marrow failure, congenital abnormalities, cancer susceptibility, and a marked cellular hypersensitivity to DNA interstrand cross-linking agents, which correlates with a defect in ability to repair this type of damage. We have previously...

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Veröffentlicht in:	The Journal of biological chemistry 1999-11, Vol.274 (46), p.32904-32908
Hauptverfasser:	McMahon, Laura W., Walsh, Christopher E., Lambert, Muriel W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blotting, Western Cell Cycle Proteins Cell Line DNA Repair DNA-Binding Proteins FANCA gene FANCA protein FANCC protein Fanconi Anemia - genetics Fanconi Anemia Complementation Group A Protein Fanconi Anemia Complementation Group C Protein Fanconi Anemia Complementation Group Proteins HeLa Cells Humans Nuclear Proteins - metabolism p230 protein Peptides - chemistry Peptides - deficiency Precipitin Tests Protein Binding Proteins - metabolism Spectrin Spectrin - deficiency Spectrin - metabolism Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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