Supra-and Extrasellar Pituitary Microadenoma as a Cause of Cushing's Disease

There has been accumulating evidence that pituitary adenomas which cause Cushing's disease are located not only in sella turcica but also in various extrasellar and intracranial regions. We describe a case of Cushing's disease caused by a supra- and extrasellar ACTH-producing microadenoma,...

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Veröffentlicht in:ENDOCRINE JOURNAL 1998, Vol.45(5), pp.631-636
Hauptverfasser: MURAKAMI, NORIHIKO, FURUTO-KATO, SUMIKO, FUJISAWA, ICHIRO, OHYAMA, KENJI, NAKAO, SATOSHI, KUWAYAMA, AKIO, KAGEYAMA, NAOKI
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container_end_page 636
container_issue 5
container_start_page 631
container_title ENDOCRINE JOURNAL
container_volume 45
creator MURAKAMI, NORIHIKO
FURUTO-KATO, SUMIKO
FUJISAWA, ICHIRO
OHYAMA, KENJI
NAKAO, SATOSHI
KUWAYAMA, AKIO
KAGEYAMA, NAOKI
description There has been accumulating evidence that pituitary adenomas which cause Cushing's disease are located not only in sella turcica but also in various extrasellar and intracranial regions. We describe a case of Cushing's disease caused by a supra- and extrasellar ACTH-producing microadenoma, which originated in the anterior pituitary and extended upward without connecting to the stalk. The pituitary microadenoma was identified and removed by transsphenoidal microsurgery. After the surgery the patient experienced complete remission. This type of pituitary microadenoma is considered to be rare, but in order to accomplish successful surgical treatment, it is necessary to consider that pituitary adenomas which cause Cushing's disease may be located in such an unusual position.
doi_str_mv 10.1507/endocrj.45.631
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We describe a case of Cushing's disease caused by a supra- and extrasellar ACTH-producing microadenoma, which originated in the anterior pituitary and extended upward without connecting to the stalk. The pituitary microadenoma was identified and removed by transsphenoidal microsurgery. After the surgery the patient experienced complete remission. This type of pituitary microadenoma is considered to be rare, but in order to accomplish successful surgical treatment, it is necessary to consider that pituitary adenomas which cause Cushing's disease may be located in such an unusual position.</abstract><cop>Japan</cop><pub>The Japan Endocrine Society</pub><pmid>10395243</pmid><doi>10.1507/endocrj.45.631</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese
subjects Adenoma - complications
Adenoma - diagnosis
Adenoma - surgery
Adrenocorticotropic Hormone - analysis
Adult
Cushing Syndrome - blood
Cushing Syndrome - etiology
Cushing's disease
Female
Humans
Immunohistochemistry
Magnetic Resonance Imaging
Microsurgery - methods
Neoplasm Invasiveness
Pituitary Gland, Anterior
Pituitary Neoplasms - complications
Pituitary Neoplasms - diagnosis
Pituitary Neoplasms - surgery
Reoperation
Supra-and extrasellar pituitary microadenoma
title Supra-and Extrasellar Pituitary Microadenoma as a Cause of Cushing's Disease
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