Accumulation of free complex-type N-glycans in MKN7 and MKN45 stomach cancer cells

During the N-glycosylation reaction, it has been shown that 'free' N-glycans are generated either from lipid-linked oligosaccharides or from misfolded glycoproteins. In both cases, occurrence of high mannose-type free glycans is well-documented, and the molecular mechanism for their catabo...

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Veröffentlicht in:	Biochemical journal 2008-07, Vol.413 (2), p.227-237
Hauptverfasser:	Ishizuka, Aya, Hashimto, Yuki, Naka, Ryosuke, Kinoshita, Mitsuhiro, Kakehi, Kazuaki, Seino, Junichi, Funakoshi, Yoko, Suzuki, Tadashi, Kameyama, Akihiko, Narimatsu, Hisashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - metabolism Cell Line, Tumor Cell Membrane - metabolism Chromatography - methods Cytosol - metabolism Electrophoresis, Capillary Gene Expression Regulation Glycosylation Humans Lysosomes - metabolism Models, Biological N-Acetylneuraminic Acid - chemistry Oligosaccharides - chemistry Oligosaccharides - metabolism Polysaccharides - chemistry Polysaccharides - metabolism Stomach Neoplasms - metabolism
Online-Zugang:	Volltext
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