Risk factors for primary open-angle glaucoma

Risk factors for primary open-angle glaucoma

To review the literature for risk factors involved in primary open-angle glaucoma (POAG). Articles and reviews studying the epidemiology and assessment of risk factors in POAG were collected from PubMed. The literature findings were divided into three categories: (1) What are the risks of developing...

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Veröffentlicht in:Journal francais d'ophtalmologie 2008-04, Vol.31 (4), p.435-444
Hauptverfasser: Bron, A, Chaine, G, Villain, M, Colin, J, Nordmann, J-P, Renard, J-P, Rouland, J-F
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Glaucoma, Open-Angle - epidemiology
Glaucoma, Open-Angle - etiology
Glaucoma, Open-Angle - genetics
Humans
Risk Factors
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container_end_page 444
container_issue 4
container_start_page 435
container_title Journal francais d'ophtalmologie
container_volume 31
creator Bron, A
Chaine, G
Villain, M
Colin, J
Nordmann, J-P
Renard, J-P
Rouland, J-F
description To review the literature for risk factors involved in primary open-angle glaucoma (POAG). Articles and reviews studying the epidemiology and assessment of risk factors in POAG were collected from PubMed. The literature findings were divided into three categories: (1) What are the risks of developing POAG in healthy subjects? Significant factors include advancing age, family history of glaucoma, African origin, and elevated intraocular pressure; (2) What are the risks of developing POAG in ocular hypertensive patients? Significant factors include age, family history of glaucoma, reduced central corneal thickness, pronounced elevated IOP, and IOP fluctuations; and (3) What are the risks for progression in known cases of POAG? Significant factors include advancing age, elevated IOP fluctuations, IOP, elevated cup-over-disk ratio, disc asymmetry, and disk hemorrhages. A working knowledge of the risk factors for developing POAG and disease progression is essential to good clinical practice. Therefore, one could ideally concentrate resources on populations at risk for developing the disease as well as more actively treat those patients at risk for progression.
doi_str_mv 10.1016/S0181-5512(08)71443-8
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subjects Glaucoma, Open-Angle - epidemiology
Glaucoma, Open-Angle - etiology
Glaucoma, Open-Angle - genetics
Humans
Risk Factors
title Risk factors for primary open-angle glaucoma
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