Fourier transform infrared imaging and small angle x-ray scattering as a combined biomolecular approach to diagnosis of breast cancer

Fourier transform infrared (FTIR) microspectroscopic imaging and small angle x-ray scattering (SAXS) were combined to investigate the supramolecular structure of collagen from 27 tissue sections from patients undergoing mastectomy, excisional biopsy, or mammoplasty. Both techniques were correlated b...

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Veröffentlicht in:	Medical physics (Lancaster) 2008-05, Vol.35 (5), p.2151-2161
Hauptverfasser:	Ooi, Geraldine J., Fox, Jane, Siu, Karen, Lewis, Rob, Bambery, Keith R., McNaughton, Don, Wood, Bayden R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption spectra Algorithms biomedical optical imaging Biopsy Breast - pathology breast cancer Breast Neoplasms - diagnosis Breast Neoplasms - pathology cancer Cluster Analysis Cluster spectra Collagen - chemistry Extracellular Matrix - metabolism Female Fourier Analysis Fourier transform infrared spectroscopy Fourier transform optics Fourier transform spectroscopy Humans infrared imaging Infrared spectra mammography Medical imaging Medical Oncology - methods molecular biophysics Nucleic acids Optical microscopy proteins Radiographic Image Interpretation, Computer-Assisted - methods Scattering, Radiation small angle x‐ray scattering Spectroscopy, Fourier Transform Infrared - methods Synchrotrons Tissues Visual imaging X-Rays X‐ray scattering
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