Contributions of PK/PD Modeling to Intravenous Anesthesia

Pharmacokinetic (PK)/pharmacodynamic (PD) modeling has made an enormous contribution to intravenous anesthesia. PK/PD models have provided us with insight into the factors affecting the onset and offset of drug effect. For example, we are now able to describe the influence of cardiac output on the d...

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Veröffentlicht in:	Clinical pharmacology and therapeutics 2008-07, Vol.84 (1), p.27-38
Hauptverfasser:	Minto, CF, Schnider, TW
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia, Intravenous - methods Anesthesia, Intravenous - trends Anesthetics, Intravenous - pharmacokinetics Anesthetics, Intravenous - pharmacology Biological and medical sciences Dose-Response Relationship, Drug Humans Medical sciences Models, Biological Pharmacology. Drug treatments
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