Long-Term Results of Percutaneous Treatment of Hydatid Liver Cysts: a Single Center 17 Years Experience
Background: Liver cystic echinococcosis is considered a relatively benign disease, nevertheless, treatment is mandatory in symptomatic cysts and recommended in active cysts because of the risk of severe complications. Surgery is still considered the gold standard treatment. In the last two decades p...
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| Veröffentlicht in: | Infection 2008-06, Vol.36 (3), p.256-261 |
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| creator | Giorgio, A. de Stefano, G. Esposito, V. Liorre, G. Di Sarno, A. Giorgio, V. Sangiovanni, V. Iannece, M. D. Mariniello, N. |
| description | Background:
Liver cystic echinococcosis is considered a relatively benign disease, nevertheless, treatment is mandatory in symptomatic cysts and recommended in active cysts because of the risk of severe complications. Surgery is still considered the gold standard treatment. In the last two decades percutaneous injection of scolicidal agents has been developed with excellent results in terms of disappearance of the cyst, very low side effects and low mortality rate.
Materials and Methods:
One hundred sixty eight patients with 225 liver cysts were studied. A total of 108 patients with 151 viable hydatid liver cysts underwent Double Percutaneous Aspiration and Injection of alcohol of the cyst without re-aspiration of the ethanol, which remained
in situ
.
Results:
The mortality rate was 0.9% (1 patient), the overall morbidity was 8.6% with only 2.5% of major side effects. The mean hospital stay was very short (2.9 days). Follow-up ranged from 14 to 204 months (median 48 months). Ultrasonography showed complete disappearance of the cyst with reconstitution of liver parenchyma in 109 out of 225 (48.4%) cysts; in the remaining cysts a solid or a liquid findings were observed in 104 (46.2%) and 12 (5.3%), respectively, with a decreased volume of 50–80%.
Conclusion:
These data show that Double Percutaneous Aspiration and Injection of alcohol for hydatid liver cysts can achieve comparable results to open surgery. The low incidence of side effects shows that this technique is safe and cost effective, compared to radical or conservative surgery. |
| doi_str_mv | 10.1007/s15010-007-7103-y |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69228629</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69228629</sourcerecordid><originalsourceid>FETCH-LOGICAL-c369t-33afeda2d3fb95e03b503616d87260ed5db8e34dac5dd54bcfdd79dbc96c09283</originalsourceid><addsrcrecordid>eNp1kU9r3DAQxUVoSDZpP0AvRfSQm5qRZMtWbmVJm8BCQ7I99CRkabw4-M9Gskv87aPFC4FCTxr0fvNmpEfIZw7fOEBxHXkOHFgqWcFBsvmErHgmNQNdyA9kBRKAlVyoc3IR4zMA5Dorzsg5L7NCcq5XZLcZ-h3bYujoI8apHSMdavqAwU2j7XGYIt0GtGOH_XhQ7mZvx8bTTfMXA13PcYw31NKnpt-1SNeJSte8oH_QhkhvX_cYGuwdfiSntW0jfjqel-T3j9vt-o5tfv28X3_fMCeVHpmUtkZvhZd1pXMEWeUgFVe-LIQC9LmvSpSZty73Ps8qV3tfaF85rRxoUcpLcrX47sPwMmEcTddEh227PMYoLUSphE7g13_A52EKfdrNCJ4rLjOhEsQXyIUhxoC12Yems2E2HMwhArNEYA7lIQIzp54vR-Op6tC_dxz_PAFiAWKS-h2G98n_d30D3suR8A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>215613426</pqid></control><display><type>article</type><title>Long-Term Results of Percutaneous Treatment of Hydatid Liver Cysts: a Single Center 17 Years Experience</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Giorgio, A. ; de Stefano, G. ; Esposito, V. ; Liorre, G. ; Di Sarno, A. ; Giorgio, V. ; Sangiovanni, V. ; Iannece, M. D. ; Mariniello, N.</creator><creatorcontrib>Giorgio, A. ; de Stefano, G. ; Esposito, V. ; Liorre, G. ; Di Sarno, A. ; Giorgio, V. ; Sangiovanni, V. ; Iannece, M. D. ; Mariniello, N.</creatorcontrib><description>Background:
Liver cystic echinococcosis is considered a relatively benign disease, nevertheless, treatment is mandatory in symptomatic cysts and recommended in active cysts because of the risk of severe complications. Surgery is still considered the gold standard treatment. In the last two decades percutaneous injection of scolicidal agents has been developed with excellent results in terms of disappearance of the cyst, very low side effects and low mortality rate.
Materials and Methods:
One hundred sixty eight patients with 225 liver cysts were studied. A total of 108 patients with 151 viable hydatid liver cysts underwent Double Percutaneous Aspiration and Injection of alcohol of the cyst without re-aspiration of the ethanol, which remained
in situ
.
Results:
The mortality rate was 0.9% (1 patient), the overall morbidity was 8.6% with only 2.5% of major side effects. The mean hospital stay was very short (2.9 days). Follow-up ranged from 14 to 204 months (median 48 months). Ultrasonography showed complete disappearance of the cyst with reconstitution of liver parenchyma in 109 out of 225 (48.4%) cysts; in the remaining cysts a solid or a liquid findings were observed in 104 (46.2%) and 12 (5.3%), respectively, with a decreased volume of 50–80%.
Conclusion:
These data show that Double Percutaneous Aspiration and Injection of alcohol for hydatid liver cysts can achieve comparable results to open surgery. The low incidence of side effects shows that this technique is safe and cost effective, compared to radical or conservative surgery.</description><identifier>ISSN: 0300-8126</identifier><identifier>EISSN: 1439-0973</identifier><identifier>DOI: 10.1007/s15010-007-7103-y</identifier><identifier>PMID: 18473119</identifier><language>eng</language><publisher>Munich: Urban & Vogel</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Brief Report ; Echinococcosis - diagnostic imaging ; Echinococcosis - drug therapy ; Echinococcosis - mortality ; Echinococcosis - parasitology ; Echinococcosis, Hepatic - diagnostic imaging ; Echinococcosis, Hepatic - drug therapy ; Echinococcosis, Hepatic - mortality ; Echinococcosis, Hepatic - parasitology ; Ethanol ; Ethanol - administration & dosage ; Ethanol - therapeutic use ; Family Medicine ; Female ; General Practice ; Humans ; Infectious Diseases ; Injection ; Injections, Intralesional ; Internal Medicine ; Liver ; Liver - diagnostic imaging ; Liver - parasitology ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Mortality ; Side effects ; Suction ; Time Factors ; Treatment Outcome ; Ultrasonography</subject><ispartof>Infection, 2008-06, Vol.36 (3), p.256-261</ispartof><rights>Urban & Vogel München 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c369t-33afeda2d3fb95e03b503616d87260ed5db8e34dac5dd54bcfdd79dbc96c09283</citedby><cites>FETCH-LOGICAL-c369t-33afeda2d3fb95e03b503616d87260ed5db8e34dac5dd54bcfdd79dbc96c09283</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s15010-007-7103-y$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s15010-007-7103-y$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18473119$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Giorgio, A.</creatorcontrib><creatorcontrib>de Stefano, G.</creatorcontrib><creatorcontrib>Esposito, V.</creatorcontrib><creatorcontrib>Liorre, G.</creatorcontrib><creatorcontrib>Di Sarno, A.</creatorcontrib><creatorcontrib>Giorgio, V.</creatorcontrib><creatorcontrib>Sangiovanni, V.</creatorcontrib><creatorcontrib>Iannece, M. D.</creatorcontrib><creatorcontrib>Mariniello, N.</creatorcontrib><title>Long-Term Results of Percutaneous Treatment of Hydatid Liver Cysts: a Single Center 17 Years Experience</title><title>Infection</title><addtitle>Infection</addtitle><addtitle>Infection</addtitle><description>Background:
Liver cystic echinococcosis is considered a relatively benign disease, nevertheless, treatment is mandatory in symptomatic cysts and recommended in active cysts because of the risk of severe complications. Surgery is still considered the gold standard treatment. In the last two decades percutaneous injection of scolicidal agents has been developed with excellent results in terms of disappearance of the cyst, very low side effects and low mortality rate.
Materials and Methods:
One hundred sixty eight patients with 225 liver cysts were studied. A total of 108 patients with 151 viable hydatid liver cysts underwent Double Percutaneous Aspiration and Injection of alcohol of the cyst without re-aspiration of the ethanol, which remained
in situ
.
Results:
The mortality rate was 0.9% (1 patient), the overall morbidity was 8.6% with only 2.5% of major side effects. The mean hospital stay was very short (2.9 days). Follow-up ranged from 14 to 204 months (median 48 months). Ultrasonography showed complete disappearance of the cyst with reconstitution of liver parenchyma in 109 out of 225 (48.4%) cysts; in the remaining cysts a solid or a liquid findings were observed in 104 (46.2%) and 12 (5.3%), respectively, with a decreased volume of 50–80%.
Conclusion:
These data show that Double Percutaneous Aspiration and Injection of alcohol for hydatid liver cysts can achieve comparable results to open surgery. The low incidence of side effects shows that this technique is safe and cost effective, compared to radical or conservative surgery.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Brief Report</subject><subject>Echinococcosis - diagnostic imaging</subject><subject>Echinococcosis - drug therapy</subject><subject>Echinococcosis - mortality</subject><subject>Echinococcosis - parasitology</subject><subject>Echinococcosis, Hepatic - diagnostic imaging</subject><subject>Echinococcosis, Hepatic - drug therapy</subject><subject>Echinococcosis, Hepatic - mortality</subject><subject>Echinococcosis, Hepatic - parasitology</subject><subject>Ethanol</subject><subject>Ethanol - administration & dosage</subject><subject>Ethanol - therapeutic use</subject><subject>Family Medicine</subject><subject>Female</subject><subject>General Practice</subject><subject>Humans</subject><subject>Infectious Diseases</subject><subject>Injection</subject><subject>Injections, Intralesional</subject><subject>Internal Medicine</subject><subject>Liver</subject><subject>Liver - diagnostic imaging</subject><subject>Liver - parasitology</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Side effects</subject><subject>Suction</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Ultrasonography</subject><issn>0300-8126</issn><issn>1439-0973</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kU9r3DAQxUVoSDZpP0AvRfSQm5qRZMtWbmVJm8BCQ7I99CRkabw4-M9Gskv87aPFC4FCTxr0fvNmpEfIZw7fOEBxHXkOHFgqWcFBsvmErHgmNQNdyA9kBRKAlVyoc3IR4zMA5Dorzsg5L7NCcq5XZLcZ-h3bYujoI8apHSMdavqAwU2j7XGYIt0GtGOH_XhQ7mZvx8bTTfMXA13PcYw31NKnpt-1SNeJSte8oH_QhkhvX_cYGuwdfiSntW0jfjqel-T3j9vt-o5tfv28X3_fMCeVHpmUtkZvhZd1pXMEWeUgFVe-LIQC9LmvSpSZty73Ps8qV3tfaF85rRxoUcpLcrX47sPwMmEcTddEh227PMYoLUSphE7g13_A52EKfdrNCJ4rLjOhEsQXyIUhxoC12Yems2E2HMwhArNEYA7lIQIzp54vR-Op6tC_dxz_PAFiAWKS-h2G98n_d30D3suR8A</recordid><startdate>20080601</startdate><enddate>20080601</enddate><creator>Giorgio, A.</creator><creator>de Stefano, G.</creator><creator>Esposito, V.</creator><creator>Liorre, G.</creator><creator>Di Sarno, A.</creator><creator>Giorgio, V.</creator><creator>Sangiovanni, V.</creator><creator>Iannece, M. D.</creator><creator>Mariniello, N.</creator><general>Urban & Vogel</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20080601</creationdate><title>Long-Term Results of Percutaneous Treatment of Hydatid Liver Cysts: a Single Center 17 Years Experience</title><author>Giorgio, A. ; de Stefano, G. ; Esposito, V. ; Liorre, G. ; Di Sarno, A. ; Giorgio, V. ; Sangiovanni, V. ; Iannece, M. D. ; Mariniello, N.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c369t-33afeda2d3fb95e03b503616d87260ed5db8e34dac5dd54bcfdd79dbc96c09283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Brief Report</topic><topic>Echinococcosis - diagnostic imaging</topic><topic>Echinococcosis - drug therapy</topic><topic>Echinococcosis - mortality</topic><topic>Echinococcosis - parasitology</topic><topic>Echinococcosis, Hepatic - diagnostic imaging</topic><topic>Echinococcosis, Hepatic - drug therapy</topic><topic>Echinococcosis, Hepatic - mortality</topic><topic>Echinococcosis, Hepatic - parasitology</topic><topic>Ethanol</topic><topic>Ethanol - administration & dosage</topic><topic>Ethanol - therapeutic use</topic><topic>Family Medicine</topic><topic>Female</topic><topic>General Practice</topic><topic>Humans</topic><topic>Infectious Diseases</topic><topic>Injection</topic><topic>Injections, Intralesional</topic><topic>Internal Medicine</topic><topic>Liver</topic><topic>Liver - diagnostic imaging</topic><topic>Liver - parasitology</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Side effects</topic><topic>Suction</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Giorgio, A.</creatorcontrib><creatorcontrib>de Stefano, G.</creatorcontrib><creatorcontrib>Esposito, V.</creatorcontrib><creatorcontrib>Liorre, G.</creatorcontrib><creatorcontrib>Di Sarno, A.</creatorcontrib><creatorcontrib>Giorgio, V.</creatorcontrib><creatorcontrib>Sangiovanni, V.</creatorcontrib><creatorcontrib>Iannece, M. D.</creatorcontrib><creatorcontrib>Mariniello, N.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing & Allied Health Database</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Infection</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Giorgio, A.</au><au>de Stefano, G.</au><au>Esposito, V.</au><au>Liorre, G.</au><au>Di Sarno, A.</au><au>Giorgio, V.</au><au>Sangiovanni, V.</au><au>Iannece, M. D.</au><au>Mariniello, N.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-Term Results of Percutaneous Treatment of Hydatid Liver Cysts: a Single Center 17 Years Experience</atitle><jtitle>Infection</jtitle><stitle>Infection</stitle><addtitle>Infection</addtitle><date>2008-06-01</date><risdate>2008</risdate><volume>36</volume><issue>3</issue><spage>256</spage><epage>261</epage><pages>256-261</pages><issn>0300-8126</issn><eissn>1439-0973</eissn><abstract>Background:
Liver cystic echinococcosis is considered a relatively benign disease, nevertheless, treatment is mandatory in symptomatic cysts and recommended in active cysts because of the risk of severe complications. Surgery is still considered the gold standard treatment. In the last two decades percutaneous injection of scolicidal agents has been developed with excellent results in terms of disappearance of the cyst, very low side effects and low mortality rate.
Materials and Methods:
One hundred sixty eight patients with 225 liver cysts were studied. A total of 108 patients with 151 viable hydatid liver cysts underwent Double Percutaneous Aspiration and Injection of alcohol of the cyst without re-aspiration of the ethanol, which remained
in situ
.
Results:
The mortality rate was 0.9% (1 patient), the overall morbidity was 8.6% with only 2.5% of major side effects. The mean hospital stay was very short (2.9 days). Follow-up ranged from 14 to 204 months (median 48 months). Ultrasonography showed complete disappearance of the cyst with reconstitution of liver parenchyma in 109 out of 225 (48.4%) cysts; in the remaining cysts a solid or a liquid findings were observed in 104 (46.2%) and 12 (5.3%), respectively, with a decreased volume of 50–80%.
Conclusion:
These data show that Double Percutaneous Aspiration and Injection of alcohol for hydatid liver cysts can achieve comparable results to open surgery. The low incidence of side effects shows that this technique is safe and cost effective, compared to radical or conservative surgery.</abstract><cop>Munich</cop><pub>Urban & Vogel</pub><pmid>18473119</pmid><doi>10.1007/s15010-007-7103-y</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Adolescent Adult Aged Aged, 80 and over Brief Report Echinococcosis - diagnostic imaging Echinococcosis - drug therapy Echinococcosis - mortality Echinococcosis - parasitology Echinococcosis, Hepatic - diagnostic imaging Echinococcosis, Hepatic - drug therapy Echinococcosis, Hepatic - mortality Echinococcosis, Hepatic - parasitology Ethanol Ethanol - administration & dosage Ethanol - therapeutic use Family Medicine Female General Practice Humans Infectious Diseases Injection Injections, Intralesional Internal Medicine Liver Liver - diagnostic imaging Liver - parasitology Male Medicine Medicine & Public Health Middle Aged Mortality Side effects Suction Time Factors Treatment Outcome Ultrasonography |
| title | Long-Term Results of Percutaneous Treatment of Hydatid Liver Cysts: a Single Center 17 Years Experience |
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