Specific down-regulation of annexin II expression in human cells interferes with cell proliferation

The protein-tyrosine kinase substrate annexin II is a growth regulated gene whose expression is increased in several human cancers. While the precise function of this protein is not understood, annexin II is proposed to be involved in multiple physiological activities, including DNA synthesis and ce...

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Veröffentlicht in:	Molecular and cellular biochemistry 1999-09, Vol.199 (1-2), p.139-147
Hauptverfasser:	Chiang, Y, Rizzino, A, Sibenaller, Z A, Wold, M S, Vishwanatha, J K
Format:	Artikel
Sprache:	eng
Schlagworte:	Annexin A2 - genetics Annexin A2 - metabolism Apoptosis Cell division Cell Division - genetics Cells, Cultured Deoxyribonucleic acid DNA DNA - biosynthesis DNA Replication DNA, Antisense - genetics Down-Regulation Gene Expression Regulation HeLa Cells - metabolism Humans Kinases Physiology Promoter Regions, Genetic Proteins RNA, Messenger - metabolism Simian virus 40 - genetics
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