The Protective Effect of EGb 761 in Isolated Ischemic/Reperfused Rat Hearts: A Link Between Cardiac Function and Nitric Oxide Production

This study was conducted to evaluate the effect of Ginkgo biloba extract (EGb 761) on the nitric oxide (NO) production in relation to the recovery of postischemic cardiac function in isolated working rat hearts. Rats were orally treated with various doses (25, 50, 75, and 100 mg/kg/day) of EGb 761 f...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1999-11, Vol.34 (5), p.711-717
Hauptverfasser:	Varga, Edit, Bodi, Annamaria, Ferdinandy, Peter, Droy-Lefaix, Marie-Therese, Blasig, Ingolf E, Tosaki, Arpad
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Dose-Response Relationship, Drug Electron Spin Resonance Spectroscopy Flavonoids - therapeutic use Free Radical Scavengers - therapeutic use General pharmacology Ginkgo biloba Heart Function Tests In Vitro Techniques Medical sciences Myocardial Ischemia - enzymology Myocardial Ischemia - metabolism Myocardial Ischemia - physiopathology Myocardial Reperfusion - methods Myocardial Reperfusion Injury - physiopathology Myocardial Reperfusion Injury - prevention & control Nitric Oxide - biosynthesis Nitric Oxide Synthase - biosynthesis Nitric Oxide Synthase Type II Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - therapeutic use Plants, Medicinal Rats Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism
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