Monocyte‐derived dendritic cells as a model for the study of HIV‐1 infection: Productive infection and phenotypic changes during culture in human serum

Dendritic cells (DC) have been implicated in the initial selection for macrophage‐tropic HIV‐1 during transmission and in the generation of high‐level virus replication during interactions with CD4 T cells. The role of DC as viral reservoirs and the extent of productive infection is unclear, but the...

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Veröffentlicht in:	Immunology and cell biology 1999-10, Vol.77 (5), p.442-450
Hauptverfasser:	Mallon, Dominic FJ, Buck, Andrew, Reece, Jeanette C, Crowe, Suzanne M, Cameron, Paul U
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Antigens, CD - metabolism Biomarkers Blood CD14 CD4 antigen Cell Culture Techniques - methods Cell Differentiation Culture Media - chemistry dendritic cell Dendritic Cells - cytology Dendritic Cells - immunology Dendritic Cells - virology Flow Cytometry Granulocyte-Macrophage Colony-Stimulating Factor HIV-1 - growth & development human immunodeficiency virus 1 Humans Immunophenotyping Interleukin-4 Macrophages - cytology mixed leukocyte reaction monocyte Monocytes - cytology Time Factors
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