4D-CT imaging with synchronized intravenous contrast injection to improve delineation of liver tumors for treatment planning
Abstract We have developed a tumor-specific protocol for the 4D-CT imaging of liver tumors using synchronized intravenous (IV) contrast injection to improve the accuracy of tumor delineation for treatment planning. Most liver metastases and cholangiocarcinomas can be imaged in the portal venous phas...
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Veröffentlicht in: | Radiotherapy and oncology 2008-06, Vol.87 (3), p.445-448 |
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creator | Beddar, A. Sam Briere, Tina Marie Balter, Peter Pan, Tinsu Tolani, Naresh Ng, Chaan Szklaruk, Janio Krishnan, Sunil |
description | Abstract We have developed a tumor-specific protocol for the 4D-CT imaging of liver tumors using synchronized intravenous (IV) contrast injection to improve the accuracy of tumor delineation for treatment planning. Most liver metastases and cholangiocarcinomas can be imaged in the portal venous phase, while hepatocellular carcinomas are most visible in the delayed phase. Combined 4D-CT imaging with synchronized IV contrast allows for both enhancement of tumor contrast and coverage over the entire breathing cycle. |
doi_str_mv | 10.1016/j.radonc.2007.12.009 |
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Sam ; Briere, Tina Marie ; Balter, Peter ; Pan, Tinsu ; Tolani, Naresh ; Ng, Chaan ; Szklaruk, Janio ; Krishnan, Sunil</creator><creatorcontrib>Beddar, A. Sam ; Briere, Tina Marie ; Balter, Peter ; Pan, Tinsu ; Tolani, Naresh ; Ng, Chaan ; Szklaruk, Janio ; Krishnan, Sunil</creatorcontrib><description>Abstract We have developed a tumor-specific protocol for the 4D-CT imaging of liver tumors using synchronized intravenous (IV) contrast injection to improve the accuracy of tumor delineation for treatment planning. Most liver metastases and cholangiocarcinomas can be imaged in the portal venous phase, while hepatocellular carcinomas are most visible in the delayed phase. Combined 4D-CT imaging with synchronized IV contrast allows for both enhancement of tumor contrast and coverage over the entire breathing cycle.</description><identifier>ISSN: 0167-8140</identifier><identifier>EISSN: 1879-0887</identifier><identifier>DOI: 10.1016/j.radonc.2007.12.009</identifier><identifier>PMID: 18194819</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>4D-CT ; Bile Duct Neoplasms - diagnostic imaging ; Bile Duct Neoplasms - radiotherapy ; Bile Ducts, Intrahepatic ; Carcinoma, Hepatocellular - diagnostic imaging ; Carcinoma, Hepatocellular - radiotherapy ; Cholangiocarcinoma - diagnostic imaging ; Cholangiocarcinoma - radiotherapy ; Contrast Media - administration & dosage ; Hematology, Oncology and Palliative Medicine ; Hepatocellular carcinoma ; Humans ; Imaging ; Injections, Intravenous ; Intravenous contrast ; Liver Neoplasms - diagnostic imaging ; Liver Neoplasms - radiotherapy ; Liver tumors ; Radiographic Image Enhancement ; Radiotherapy Planning, Computer-Assisted ; Tomography, X-Ray Computed ; Triiodobenzoic Acids - administration & dosage</subject><ispartof>Radiotherapy and oncology, 2008-06, Vol.87 (3), p.445-448</ispartof><rights>Elsevier Ireland Ltd</rights><rights>2007 Elsevier Ireland Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-4d7391e9f0d5b183e79db83886670e3cfeac3464d7506bf127f224b4ee8226b3</citedby><cites>FETCH-LOGICAL-c415t-4d7391e9f0d5b183e79db83886670e3cfeac3464d7506bf127f224b4ee8226b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.radonc.2007.12.009$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27922,27923,45993</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18194819$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Beddar, A. Sam</creatorcontrib><creatorcontrib>Briere, Tina Marie</creatorcontrib><creatorcontrib>Balter, Peter</creatorcontrib><creatorcontrib>Pan, Tinsu</creatorcontrib><creatorcontrib>Tolani, Naresh</creatorcontrib><creatorcontrib>Ng, Chaan</creatorcontrib><creatorcontrib>Szklaruk, Janio</creatorcontrib><creatorcontrib>Krishnan, Sunil</creatorcontrib><title>4D-CT imaging with synchronized intravenous contrast injection to improve delineation of liver tumors for treatment planning</title><title>Radiotherapy and oncology</title><addtitle>Radiother Oncol</addtitle><description>Abstract We have developed a tumor-specific protocol for the 4D-CT imaging of liver tumors using synchronized intravenous (IV) contrast injection to improve the accuracy of tumor delineation for treatment planning. Most liver metastases and cholangiocarcinomas can be imaged in the portal venous phase, while hepatocellular carcinomas are most visible in the delayed phase. Combined 4D-CT imaging with synchronized IV contrast allows for both enhancement of tumor contrast and coverage over the entire breathing cycle.</description><subject>4D-CT</subject><subject>Bile Duct Neoplasms - diagnostic imaging</subject><subject>Bile Duct Neoplasms - radiotherapy</subject><subject>Bile Ducts, Intrahepatic</subject><subject>Carcinoma, Hepatocellular - diagnostic imaging</subject><subject>Carcinoma, Hepatocellular - radiotherapy</subject><subject>Cholangiocarcinoma - diagnostic imaging</subject><subject>Cholangiocarcinoma - radiotherapy</subject><subject>Contrast Media - administration & dosage</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Hepatocellular carcinoma</subject><subject>Humans</subject><subject>Imaging</subject><subject>Injections, Intravenous</subject><subject>Intravenous contrast</subject><subject>Liver Neoplasms - diagnostic imaging</subject><subject>Liver Neoplasms - radiotherapy</subject><subject>Liver tumors</subject><subject>Radiographic Image Enhancement</subject><subject>Radiotherapy Planning, Computer-Assisted</subject><subject>Tomography, X-Ray Computed</subject><subject>Triiodobenzoic Acids - administration & dosage</subject><issn>0167-8140</issn><issn>1879-0887</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkcuO0zAUhi0EYjoDb4CQV-wSjp2LnQ0S6nCTRmJB91binMw4JHax046KeHhOaCUkNiws28f_fy6fGXslIBcg6rdjHts-eJtLAJULmQM0T9hGaNVkoLV6yjYkU5kWJVyx65RGAJBQqOfsSmjRlLQ27Fd5m2133M3tvfP3_NEtDzydvH2Iwbuf2HPnl9ge0YdD4jasl7RQcES7uOD5Esi7j-GIvMfJeWz_hMPAJ3fEyJfDHGLiQ6BjpMcZ_cL3U-s9lXvBng3tlPDlZb9hu48fdtvP2d3XT1-27-8yW4pqycpeFY3AZoC-6oQuUDV9pwut61oBFnbA1hZlTbIK6m4QUg1Sll2JqKWsu-KGvTmnpT5_HDAtZnbJ4kRdII1l6kZKKSpBwvIstDGkFHEw-0hk4skIMCt0M5ozdLNCN0Iagk6215f8h27G_q_pQpkE784CpCGPDqNJ1qG32LtIHE0f3P8q_JvAEmtn2-k7njCN4RA9ATTCJDKYb-vHr_8OCqCuK1n8BqBNrGE</recordid><startdate>20080601</startdate><enddate>20080601</enddate><creator>Beddar, A. Sam</creator><creator>Briere, Tina Marie</creator><creator>Balter, Peter</creator><creator>Pan, Tinsu</creator><creator>Tolani, Naresh</creator><creator>Ng, Chaan</creator><creator>Szklaruk, Janio</creator><creator>Krishnan, Sunil</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080601</creationdate><title>4D-CT imaging with synchronized intravenous contrast injection to improve delineation of liver tumors for treatment planning</title><author>Beddar, A. Sam ; Briere, Tina Marie ; Balter, Peter ; Pan, Tinsu ; Tolani, Naresh ; Ng, Chaan ; Szklaruk, Janio ; Krishnan, Sunil</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-4d7391e9f0d5b183e79db83886670e3cfeac3464d7506bf127f224b4ee8226b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>4D-CT</topic><topic>Bile Duct Neoplasms - diagnostic imaging</topic><topic>Bile Duct Neoplasms - radiotherapy</topic><topic>Bile Ducts, Intrahepatic</topic><topic>Carcinoma, Hepatocellular - diagnostic imaging</topic><topic>Carcinoma, Hepatocellular - radiotherapy</topic><topic>Cholangiocarcinoma - diagnostic imaging</topic><topic>Cholangiocarcinoma - radiotherapy</topic><topic>Contrast Media - administration & dosage</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Hepatocellular carcinoma</topic><topic>Humans</topic><topic>Imaging</topic><topic>Injections, Intravenous</topic><topic>Intravenous contrast</topic><topic>Liver Neoplasms - diagnostic imaging</topic><topic>Liver Neoplasms - radiotherapy</topic><topic>Liver tumors</topic><topic>Radiographic Image Enhancement</topic><topic>Radiotherapy Planning, Computer-Assisted</topic><topic>Tomography, X-Ray Computed</topic><topic>Triiodobenzoic Acids - administration & dosage</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Beddar, A. Sam</creatorcontrib><creatorcontrib>Briere, Tina Marie</creatorcontrib><creatorcontrib>Balter, Peter</creatorcontrib><creatorcontrib>Pan, Tinsu</creatorcontrib><creatorcontrib>Tolani, Naresh</creatorcontrib><creatorcontrib>Ng, Chaan</creatorcontrib><creatorcontrib>Szklaruk, Janio</creatorcontrib><creatorcontrib>Krishnan, Sunil</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Radiotherapy and oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Beddar, A. Sam</au><au>Briere, Tina Marie</au><au>Balter, Peter</au><au>Pan, Tinsu</au><au>Tolani, Naresh</au><au>Ng, Chaan</au><au>Szklaruk, Janio</au><au>Krishnan, Sunil</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>4D-CT imaging with synchronized intravenous contrast injection to improve delineation of liver tumors for treatment planning</atitle><jtitle>Radiotherapy and oncology</jtitle><addtitle>Radiother Oncol</addtitle><date>2008-06-01</date><risdate>2008</risdate><volume>87</volume><issue>3</issue><spage>445</spage><epage>448</epage><pages>445-448</pages><issn>0167-8140</issn><eissn>1879-0887</eissn><abstract>Abstract We have developed a tumor-specific protocol for the 4D-CT imaging of liver tumors using synchronized intravenous (IV) contrast injection to improve the accuracy of tumor delineation for treatment planning. Most liver metastases and cholangiocarcinomas can be imaged in the portal venous phase, while hepatocellular carcinomas are most visible in the delayed phase. Combined 4D-CT imaging with synchronized IV contrast allows for both enhancement of tumor contrast and coverage over the entire breathing cycle.</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>18194819</pmid><doi>10.1016/j.radonc.2007.12.009</doi><tpages>4</tpages></addata></record> |
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subjects | 4D-CT Bile Duct Neoplasms - diagnostic imaging Bile Duct Neoplasms - radiotherapy Bile Ducts, Intrahepatic Carcinoma, Hepatocellular - diagnostic imaging Carcinoma, Hepatocellular - radiotherapy Cholangiocarcinoma - diagnostic imaging Cholangiocarcinoma - radiotherapy Contrast Media - administration & dosage Hematology, Oncology and Palliative Medicine Hepatocellular carcinoma Humans Imaging Injections, Intravenous Intravenous contrast Liver Neoplasms - diagnostic imaging Liver Neoplasms - radiotherapy Liver tumors Radiographic Image Enhancement Radiotherapy Planning, Computer-Assisted Tomography, X-Ray Computed Triiodobenzoic Acids - administration & dosage |
title | 4D-CT imaging with synchronized intravenous contrast injection to improve delineation of liver tumors for treatment planning |
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