Farnesylation of Ras is important for the interaction with phosphoinositide 3‐kinase γ

The correct functioning of Ras proteins requires post‐translational modification of the GTP hydrolases (GTPases). These modifications provide hydrophobic moieties that lead to the attachment of Ras to the inner side of the plasma membrane. In this study we investigated the role of Ras processing in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of biochemistry 1999-11, Vol.266 (1), p.70-82
Hauptverfasser:	Rubio, Ignacio, Wittig, Ute, Meyer, Claudia, Heinze, Regina, Kadereit, Dieter, Waldmann, Herbert, Downward, Julian, Wetzker, Reinhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals farnesylation GTP Phosphohydrolases - metabolism GTPase-Activating Proteins - metabolism Nucleopolyhedrovirus - genetics Phosphatidylinositol 3-Kinases - metabolism phosphoinositide 3‐kinase post‐translational modifications Protein Binding Protein Prenylation Protein Processing, Post-Translational Proto-Oncogene Proteins c-raf - metabolism Proto-Oncogene Proteins p21(ras) - metabolism Ras ras Proteins - metabolism Recombinant Fusion Proteins - metabolism Spodoptera
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!