Cystatin C: current step and future prospects
Cystatin C is a low molecular weight-protein, which may replace creatinine for the evaluation of renal function, particularly in the clinical settings where the relationship between creatinine production and muscular mass impairs the clinical performance of creatinine. This paper intends to summariz...
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Veröffentlicht in: | Annales de biologie clinique (Paris) 2008-05, Vol.66 (3), p.301-323 |
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creator | Séronie-Vivien, S Delanaye, P Pieroni, L Mariat, C Froissart, M Cristol, J-P |
description | Cystatin C is a low molecular weight-protein, which may replace creatinine for the evaluation of renal function, particularly in the clinical settings where the relationship between creatinine production and muscular mass impairs the clinical performance of creatinine. This paper intends to summarize the current knowledge about the physiology of cystatin C and about its use as a renal marker, alone or within formulas developed to estimate the glomerular filtration rate. Moreover, this paper reviews the recent data about potential other applications of cystatin C, especially in cardiology, in oncology and in clinical pharmacology. |
doi_str_mv | 10.1684/abc.2008.0227 |
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This paper intends to summarize the current knowledge about the physiology of cystatin C and about its use as a renal marker, alone or within formulas developed to estimate the glomerular filtration rate. Moreover, this paper reviews the recent data about potential other applications of cystatin C, especially in cardiology, in oncology and in clinical pharmacology.</description><identifier>ISSN: 0003-3898</identifier><identifier>DOI: 10.1684/abc.2008.0227</identifier><identifier>PMID: 18558570</identifier><language>fre</language><publisher>France</publisher><subject>Biomarkers - blood ; Cardiovascular Diseases - blood ; Cardiovascular Diseases - diagnosis ; Cystatin C ; Cystatins - blood ; Glomerular Filtration Rate ; Humans ; Kidney Diseases - blood ; Kidney Diseases - diagnosis ; Neoplasms - blood ; Neoplasms - diagnosis</subject><ispartof>Annales de biologie clinique (Paris), 2008-05, Vol.66 (3), p.301-323</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18558570$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Séronie-Vivien, S</creatorcontrib><creatorcontrib>Delanaye, P</creatorcontrib><creatorcontrib>Pieroni, L</creatorcontrib><creatorcontrib>Mariat, C</creatorcontrib><creatorcontrib>Froissart, M</creatorcontrib><creatorcontrib>Cristol, J-P</creatorcontrib><creatorcontrib>Groupe de travail "Biologie des fonctions rénales et de l'insuffisance rénale" de la SFBC</creatorcontrib><title>Cystatin C: current step and future prospects</title><title>Annales de biologie clinique (Paris)</title><addtitle>Ann Biol Clin (Paris)</addtitle><description>Cystatin C is a low molecular weight-protein, which may replace creatinine for the evaluation of renal function, particularly in the clinical settings where the relationship between creatinine production and muscular mass impairs the clinical performance of creatinine. This paper intends to summarize the current knowledge about the physiology of cystatin C and about its use as a renal marker, alone or within formulas developed to estimate the glomerular filtration rate. Moreover, this paper reviews the recent data about potential other applications of cystatin C, especially in cardiology, in oncology and in clinical pharmacology.</description><subject>Biomarkers - blood</subject><subject>Cardiovascular Diseases - blood</subject><subject>Cardiovascular Diseases - diagnosis</subject><subject>Cystatin C</subject><subject>Cystatins - blood</subject><subject>Glomerular Filtration Rate</subject><subject>Humans</subject><subject>Kidney Diseases - blood</subject><subject>Kidney Diseases - diagnosis</subject><subject>Neoplasms - blood</subject><subject>Neoplasms - diagnosis</subject><issn>0003-3898</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1jz1PwzAURT2AaCmMrCgTW8KzHdvPbCiigFSJBebIiW0pKEmDP4b-eyJRlnuXo3N1CbmjUFGJ9aPp-ooBYAWMqQuyBQBectS4IdcxfgNQhpxfkQ1FIVAo2JKyOcVk0jAXzVPR5xDcnIqY3FKY2RY-pxxcsYRjXFyf4g259GaM7vbcO_K1f_ls3srDx-t783woF8p1KtdArKnhUktACarzAlhvQSpGpRC0E5YjVVxbpNA58MLo3lFfo-JWeL4jD3_edfknu5jaaYi9G0czu2OOrdSrRwGu4P0ZzN3kbLuEYTLh1P4f5L_7jU3p</recordid><startdate>200805</startdate><enddate>200805</enddate><creator>Séronie-Vivien, S</creator><creator>Delanaye, P</creator><creator>Pieroni, L</creator><creator>Mariat, C</creator><creator>Froissart, M</creator><creator>Cristol, J-P</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200805</creationdate><title>Cystatin C: current step and future prospects</title><author>Séronie-Vivien, S ; Delanaye, P ; Pieroni, L ; Mariat, C ; Froissart, M ; Cristol, J-P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p139t-1398841a369608607bf502cd067216551b5d381739d810be0f5a9ce1f4873d5f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>fre</language><creationdate>2008</creationdate><topic>Biomarkers - blood</topic><topic>Cardiovascular Diseases - blood</topic><topic>Cardiovascular Diseases - diagnosis</topic><topic>Cystatin C</topic><topic>Cystatins - blood</topic><topic>Glomerular Filtration Rate</topic><topic>Humans</topic><topic>Kidney Diseases - blood</topic><topic>Kidney Diseases - diagnosis</topic><topic>Neoplasms - blood</topic><topic>Neoplasms - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Séronie-Vivien, S</creatorcontrib><creatorcontrib>Delanaye, P</creatorcontrib><creatorcontrib>Pieroni, L</creatorcontrib><creatorcontrib>Mariat, C</creatorcontrib><creatorcontrib>Froissart, M</creatorcontrib><creatorcontrib>Cristol, J-P</creatorcontrib><creatorcontrib>Groupe de travail "Biologie des fonctions rénales et de l'insuffisance rénale" de la SFBC</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Annales de biologie clinique (Paris)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Séronie-Vivien, S</au><au>Delanaye, P</au><au>Pieroni, L</au><au>Mariat, C</au><au>Froissart, M</au><au>Cristol, J-P</au><aucorp>Groupe de travail "Biologie des fonctions rénales et de l'insuffisance rénale" de la SFBC</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cystatin C: current step and future prospects</atitle><jtitle>Annales de biologie clinique (Paris)</jtitle><addtitle>Ann Biol Clin (Paris)</addtitle><date>2008-05</date><risdate>2008</risdate><volume>66</volume><issue>3</issue><spage>301</spage><epage>323</epage><pages>301-323</pages><issn>0003-3898</issn><abstract>Cystatin C is a low molecular weight-protein, which may replace creatinine for the evaluation of renal function, particularly in the clinical settings where the relationship between creatinine production and muscular mass impairs the clinical performance of creatinine. This paper intends to summarize the current knowledge about the physiology of cystatin C and about its use as a renal marker, alone or within formulas developed to estimate the glomerular filtration rate. Moreover, this paper reviews the recent data about potential other applications of cystatin C, especially in cardiology, in oncology and in clinical pharmacology.</abstract><cop>France</cop><pmid>18558570</pmid><doi>10.1684/abc.2008.0227</doi><tpages>23</tpages></addata></record> |
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subjects | Biomarkers - blood Cardiovascular Diseases - blood Cardiovascular Diseases - diagnosis Cystatin C Cystatins - blood Glomerular Filtration Rate Humans Kidney Diseases - blood Kidney Diseases - diagnosis Neoplasms - blood Neoplasms - diagnosis |
title | Cystatin C: current step and future prospects |
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