Expression of Activin A and Follistatin Core Proteins by Human Prostate Tumor Cell Lines

Activin and follistatin (FS) messenger RNA and protein are expressed and localized to human prostate tissue from men with high grade cancer and to human prostate tumor cell lines LNCaP, DU145, and PC3. Although activin A induces apoptosis and inhibits cell proliferation in LNCaP cells, PC3 cells are...

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Veröffentlicht in:	Endocrinology (Philadelphia) 1999-11, Vol.140 (11), p.5303-5309
Hauptverfasser:	McPherson, Stephen J, Mellor, Sally L, Wang, Hong, Evans, Lee W, Groome, Nigel P, Risbridger, Gail P
Format:	Artikel
Sprache:	eng
Schlagworte:	Activin Activins Alternative Splicing Apoptosis Autocrine signalling Blotting, Western Cell culture Cell proliferation Culture media Culture Media, Conditioned Enzyme-Linked Immunosorbent Assay Follistatin Gene Expression Glycoproteins - analysis Glycoproteins - biosynthesis Glycoproteins - genetics Humans Immunoassays Immunocytochemistry Immunohistochemistry Inhibins - analysis Inhibins - biosynthesis Inhibins - genetics Male Prostate Prostate cancer Prostatic Neoplasms - chemistry Prostatic Neoplasms - metabolism Proteins RNA, Messenger - analysis Tumor cell lines Tumor cells Tumor Cells, Cultured Tumors Western blotting
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