Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE)

The objective of the study was that the regulatory T cells (Treg) that specialize in the suppression of immune responses might be critically involved in the pathogenesis of autoimmune disease. As for systemic lupus erythematosus (SLE), however, published data concerning Treg phenotype and function a...

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Veröffentlicht in:International immunology 2008-07, Vol.20 (7), p.861-868
Hauptverfasser: Bonelli, Michael, Savitskaya, Anastasia, von Dalwigk, Karolina, Steiner, Carl Walter, Aletaha, Daniel, Smolen, Josef S., Scheinecker, Clemens
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Sprache:eng
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