Metabolic and mitogenic effects of IGF-II in rainbow trout ( Oncorhynchus mykiss ) myocytes in culture and the role of IGF-II in the PI3K/Akt and MAPK signalling pathways

Abstract Primary cultures of rainbow trout skeletal muscle cells were used to examine the role of insulin-like growth factor II (IGF-II) in fish muscle metabolism and growth, and to compare its main signal transduction pathways with those of IGF-I. IGF-II stimulated 2-deoxy- d -glucose (2-DG) uptake...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	General and comparative endocrinology 2008-06, Vol.157 (2), p.116-124
Hauptverfasser:	Codina, Marta, García de la serrana, Daniel, Sánchez-Gurmaches, Joan, Montserrat, Núria, Chistyakova, Oxana, Navarro, Isabel, Gutiérrez, Joaquim
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport - drug effects Blotting, Western Brackish Cell Proliferation - drug effects Cells, Cultured Deoxyglucose - metabolism Endocrinology & Metabolism Freshwater Insulin growth factor II Insulin-Like Growth Factor I - pharmacology Insulin-Like Growth Factor II - pharmacology MAPK Marine Metabolic effects Mitogen-Activated Protein Kinases - metabolism Muscle Cells - cytology Muscle Cells - drug effects Muscle Cells - metabolism Muscle, Skeletal - cytology Muscle, Skeletal - drug effects Muscle, Skeletal - metabolism Oncorhynchus mykiss Phosphatidylinositol 3-Kinases - metabolism Phosphorylation - drug effects PI3K/Akt Proliferation Proto-Oncogene Proteins c-akt - metabolism Rainbow trout Signal Transduction - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!