Molecular Cloning and Characterization of a Novel Repeat-containing Leishmania major Gene,ppg1, That Encodes a Membrane-associated Form of Proteophosphoglycan with a Putative Glycosylphosphatidylinositol Anchor

Leishmania parasites secrete a variety of proteins that are modified by phosphoglycan chains structurally similar to those of the cell surface glycolipid lipophosphoglycan. These proteins are collectively called proteophosphoglycans. We report here the cloning and sequencing of a novel Leishmania ma...

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Veröffentlicht in:	The Journal of biological chemistry 1999-10, Vol.274 (44), p.31410-31420
Hauptverfasser:	Ilg, Thomas, Montgomery, Jacqui, Stierhof, York-Dieter, Handman, Emanuela
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Genes, Protozoan Genomic Library Glycosphingolipids - genetics Glycosylation Glycosylphosphatidylinositols Host-Parasite Interactions Leishmania major Leishmania major - genetics Membrane Proteins - genetics Membrane Proteins - ultrastructure Molecular Sequence Data ppg1 gene Protein Sorting Signals Proteoglycans - genetics Proteoglycans - ultrastructure proteophosphoglycan proteophosphoglycans Protozoan Proteins Repetitive Sequences, Amino Acid Restriction Mapping Sequence Homology, Amino Acid
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