Estimating the prevalence of borderline personality disorder in psychiatric outpatients using a two-phase procedure
Abstract The prevalence of borderline personality disorder (BPD) in outpatient clinics varies greatly (7%-27%) depending on the setting and methodology. We examined the cross-sectional rate of BPD in a general adult outpatient university clinic using a 2-phase procedure: (1) we screened all register...
Gespeichert in:
Veröffentlicht in: | Comprehensive psychiatry 2008-07, Vol.49 (4), p.380-386 |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 386 |
---|---|
container_issue | 4 |
container_start_page | 380 |
container_title | Comprehensive psychiatry |
container_volume | 49 |
creator | Korzekwa, Marilyn I Dell, Paul F Links, Paul S Thabane, Lehana Webb, Steven P |
description | Abstract The prevalence of borderline personality disorder (BPD) in outpatient clinics varies greatly (7%-27%) depending on the setting and methodology. We examined the cross-sectional rate of BPD in a general adult outpatient university clinic using a 2-phase procedure: (1) we screened all registered patients with the self-report SCID-II-PQ and (2) we administered the Revised Diagnostic Interview for Borderlines (DIB-R). Sixty-six percent (239/360) of the clinic patients completed the screening: About 72.4% (173/239) (95% confidence interval [CI] = 66.7%, 78.1%) were positive for BPD on the Structured Clinical Interview for DSM-IV Personality Disorders–Patient Questionnaire (SCID-II-PQ), and 22.6% (54/239) (95% CI = 17.3%, 27.9%) were positive for BPD on the DIB-R. Our BPD rate was somewhat higher than recent semistructured interview studies (9%-18%). We believe this is due, in part, to our cross-sectional design and our decision not to exclude acute Axis I disorders. Mostly, however, we believe that our 22.6% incidence of BPD arises from the high morbidity of our sample. Demographic data from 130 of 131 DIB-R completers reveal the following: mean age was 40.2 years, 75.4% were female, most patients were unable to work, and they averaged 3.8 lifetime hospitalizations. |
doi_str_mv | 10.1016/j.comppsych.2008.01.007 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69206374</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0010440X08000278</els_id><sourcerecordid>69206374</sourcerecordid><originalsourceid>FETCH-LOGICAL-c482t-d82c00b5e27be2a66aef1b0bff2cbc753c26b48ce8ba3a1bac922743cb5e9ceb3</originalsourceid><addsrcrecordid>eNqNkk9v1DAQxS0EosvCV4BIqNyyjJ1_zgWpqkqLVIkDIHGzbGfCesnGweMU7bfH6a5aqSdOPszvvfHMG8becdhw4PXH3cb6_TTRwW43AkBugG8AmmdsxatC5LKQ5XO2AuCQlyX8PGOviHaQQCnLl-yMy6qqoGpXjK4our2ObvyVxS1mU8A7PeBoMfN9ZnzoMAxuTAUM5Ec9uHjIOkf3hcyN2f0fnI7B2czPcUpWOEbKZlosdRb_-nzaalqsvcVuDviavej1QPjm9K7Zj89X3y9v8tuv118uL25zW0oR804KC2AqFI1BoetaY88NmL4X1timKqyoTSktSqMLzY22rRBNWdgkaS2aYs0-HH1T5z8zUlR7RxaHQY_oZ1J1K6AukmLN3j8Bd34OaVhSHEQrZc3bIlHNkbLBEwXs1RTS6sIhQWpJRe3UQypqSUUBVymVpHx78p_NHrtH3SmGBJyfAE1WD33Qo3X0wAkoa2hAJu7iyGFa253DoMi6JazOBbRRdd79x2c-PfGwKWCX2v7GA9Lj5IqEAvVtOaLlhkCm-xGNLP4BkDfIKQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1029886193</pqid></control><display><type>article</type><title>Estimating the prevalence of borderline personality disorder in psychiatric outpatients using a two-phase procedure</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Korzekwa, Marilyn I ; Dell, Paul F ; Links, Paul S ; Thabane, Lehana ; Webb, Steven P</creator><creatorcontrib>Korzekwa, Marilyn I ; Dell, Paul F ; Links, Paul S ; Thabane, Lehana ; Webb, Steven P</creatorcontrib><description>Abstract The prevalence of borderline personality disorder (BPD) in outpatient clinics varies greatly (7%-27%) depending on the setting and methodology. We examined the cross-sectional rate of BPD in a general adult outpatient university clinic using a 2-phase procedure: (1) we screened all registered patients with the self-report SCID-II-PQ and (2) we administered the Revised Diagnostic Interview for Borderlines (DIB-R). Sixty-six percent (239/360) of the clinic patients completed the screening: About 72.4% (173/239) (95% confidence interval [CI] = 66.7%, 78.1%) were positive for BPD on the Structured Clinical Interview for DSM-IV Personality Disorders–Patient Questionnaire (SCID-II-PQ), and 22.6% (54/239) (95% CI = 17.3%, 27.9%) were positive for BPD on the DIB-R. Our BPD rate was somewhat higher than recent semistructured interview studies (9%-18%). We believe this is due, in part, to our cross-sectional design and our decision not to exclude acute Axis I disorders. Mostly, however, we believe that our 22.6% incidence of BPD arises from the high morbidity of our sample. Demographic data from 130 of 131 DIB-R completers reveal the following: mean age was 40.2 years, 75.4% were female, most patients were unable to work, and they averaged 3.8 lifetime hospitalizations.</description><identifier>ISSN: 0010-440X</identifier><identifier>EISSN: 1532-8384</identifier><identifier>DOI: 10.1016/j.comppsych.2008.01.007</identifier><identifier>PMID: 18555059</identifier><identifier>CODEN: COPYAV</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject><![CDATA[Adult ; Adult and adolescent clinical studies ; Ambulatory Care Facilities - statistics & numerical data ; Biological and medical sciences ; Borderline Personality Disorder - diagnosis ; Borderline Personality Disorder - epidemiology ; Borderline Personality Disorder - psychology ; Clinics ; Cross-Sectional Studies ; Disability Evaluation ; Female ; Health Surveys ; Hospitals, University - statistics & numerical data ; Humans ; Interview, Psychological ; Interviews ; Male ; Mass Screening ; Medical sciences ; Middle Aged ; Ontario ; Patient Readmission - statistics & numerical data ; Personality disorders ; Personality Inventory - statistics & numerical data ; Psychiatric Department, Hospital - statistics & numerical data ; Psychiatry ; Psychology. Psychoanalysis. Psychiatry ; Psychometrics - statistics & numerical data ; Psychopathology. Psychiatry ; Questionnaires ; Reproducibility of Results ; Self destructive behavior ; Studies ; Suicides & suicide attempts ; Therapists]]></subject><ispartof>Comprehensive psychiatry, 2008-07, Vol.49 (4), p.380-386</ispartof><rights>Elsevier Inc.</rights><rights>2008 Elsevier Inc.</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c482t-d82c00b5e27be2a66aef1b0bff2cbc753c26b48ce8ba3a1bac922743cb5e9ceb3</citedby><cites>FETCH-LOGICAL-c482t-d82c00b5e27be2a66aef1b0bff2cbc753c26b48ce8ba3a1bac922743cb5e9ceb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0010440X08000278$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20460708$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18555059$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Korzekwa, Marilyn I</creatorcontrib><creatorcontrib>Dell, Paul F</creatorcontrib><creatorcontrib>Links, Paul S</creatorcontrib><creatorcontrib>Thabane, Lehana</creatorcontrib><creatorcontrib>Webb, Steven P</creatorcontrib><title>Estimating the prevalence of borderline personality disorder in psychiatric outpatients using a two-phase procedure</title><title>Comprehensive psychiatry</title><addtitle>Compr Psychiatry</addtitle><description>Abstract The prevalence of borderline personality disorder (BPD) in outpatient clinics varies greatly (7%-27%) depending on the setting and methodology. We examined the cross-sectional rate of BPD in a general adult outpatient university clinic using a 2-phase procedure: (1) we screened all registered patients with the self-report SCID-II-PQ and (2) we administered the Revised Diagnostic Interview for Borderlines (DIB-R). Sixty-six percent (239/360) of the clinic patients completed the screening: About 72.4% (173/239) (95% confidence interval [CI] = 66.7%, 78.1%) were positive for BPD on the Structured Clinical Interview for DSM-IV Personality Disorders–Patient Questionnaire (SCID-II-PQ), and 22.6% (54/239) (95% CI = 17.3%, 27.9%) were positive for BPD on the DIB-R. Our BPD rate was somewhat higher than recent semistructured interview studies (9%-18%). We believe this is due, in part, to our cross-sectional design and our decision not to exclude acute Axis I disorders. Mostly, however, we believe that our 22.6% incidence of BPD arises from the high morbidity of our sample. Demographic data from 130 of 131 DIB-R completers reveal the following: mean age was 40.2 years, 75.4% were female, most patients were unable to work, and they averaged 3.8 lifetime hospitalizations.</description><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Ambulatory Care Facilities - statistics & numerical data</subject><subject>Biological and medical sciences</subject><subject>Borderline Personality Disorder - diagnosis</subject><subject>Borderline Personality Disorder - epidemiology</subject><subject>Borderline Personality Disorder - psychology</subject><subject>Clinics</subject><subject>Cross-Sectional Studies</subject><subject>Disability Evaluation</subject><subject>Female</subject><subject>Health Surveys</subject><subject>Hospitals, University - statistics & numerical data</subject><subject>Humans</subject><subject>Interview, Psychological</subject><subject>Interviews</subject><subject>Male</subject><subject>Mass Screening</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Ontario</subject><subject>Patient Readmission - statistics & numerical data</subject><subject>Personality disorders</subject><subject>Personality Inventory - statistics & numerical data</subject><subject>Psychiatric Department, Hospital - statistics & numerical data</subject><subject>Psychiatry</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychometrics - statistics & numerical data</subject><subject>Psychopathology. Psychiatry</subject><subject>Questionnaires</subject><subject>Reproducibility of Results</subject><subject>Self destructive behavior</subject><subject>Studies</subject><subject>Suicides & suicide attempts</subject><subject>Therapists</subject><issn>0010-440X</issn><issn>1532-8384</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkk9v1DAQxS0EosvCV4BIqNyyjJ1_zgWpqkqLVIkDIHGzbGfCesnGweMU7bfH6a5aqSdOPszvvfHMG8becdhw4PXH3cb6_TTRwW43AkBugG8AmmdsxatC5LKQ5XO2AuCQlyX8PGOviHaQQCnLl-yMy6qqoGpXjK4our2ObvyVxS1mU8A7PeBoMfN9ZnzoMAxuTAUM5Ec9uHjIOkf3hcyN2f0fnI7B2czPcUpWOEbKZlosdRb_-nzaalqsvcVuDviavej1QPjm9K7Zj89X3y9v8tuv118uL25zW0oR804KC2AqFI1BoetaY88NmL4X1timKqyoTSktSqMLzY22rRBNWdgkaS2aYs0-HH1T5z8zUlR7RxaHQY_oZ1J1K6AukmLN3j8Bd34OaVhSHEQrZc3bIlHNkbLBEwXs1RTS6sIhQWpJRe3UQypqSUUBVymVpHx78p_NHrtH3SmGBJyfAE1WD33Qo3X0wAkoa2hAJu7iyGFa253DoMi6JazOBbRRdd79x2c-PfGwKWCX2v7GA9Lj5IqEAvVtOaLlhkCm-xGNLP4BkDfIKQ</recordid><startdate>20080701</startdate><enddate>20080701</enddate><creator>Korzekwa, Marilyn I</creator><creator>Dell, Paul F</creator><creator>Links, Paul S</creator><creator>Thabane, Lehana</creator><creator>Webb, Steven P</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20080701</creationdate><title>Estimating the prevalence of borderline personality disorder in psychiatric outpatients using a two-phase procedure</title><author>Korzekwa, Marilyn I ; Dell, Paul F ; Links, Paul S ; Thabane, Lehana ; Webb, Steven P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c482t-d82c00b5e27be2a66aef1b0bff2cbc753c26b48ce8ba3a1bac922743cb5e9ceb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Ambulatory Care Facilities - statistics & numerical data</topic><topic>Biological and medical sciences</topic><topic>Borderline Personality Disorder - diagnosis</topic><topic>Borderline Personality Disorder - epidemiology</topic><topic>Borderline Personality Disorder - psychology</topic><topic>Clinics</topic><topic>Cross-Sectional Studies</topic><topic>Disability Evaluation</topic><topic>Female</topic><topic>Health Surveys</topic><topic>Hospitals, University - statistics & numerical data</topic><topic>Humans</topic><topic>Interview, Psychological</topic><topic>Interviews</topic><topic>Male</topic><topic>Mass Screening</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Ontario</topic><topic>Patient Readmission - statistics & numerical data</topic><topic>Personality disorders</topic><topic>Personality Inventory - statistics & numerical data</topic><topic>Psychiatric Department, Hospital - statistics & numerical data</topic><topic>Psychiatry</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychometrics - statistics & numerical data</topic><topic>Psychopathology. Psychiatry</topic><topic>Questionnaires</topic><topic>Reproducibility of Results</topic><topic>Self destructive behavior</topic><topic>Studies</topic><topic>Suicides & suicide attempts</topic><topic>Therapists</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Korzekwa, Marilyn I</creatorcontrib><creatorcontrib>Dell, Paul F</creatorcontrib><creatorcontrib>Links, Paul S</creatorcontrib><creatorcontrib>Thabane, Lehana</creatorcontrib><creatorcontrib>Webb, Steven P</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Comprehensive psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Korzekwa, Marilyn I</au><au>Dell, Paul F</au><au>Links, Paul S</au><au>Thabane, Lehana</au><au>Webb, Steven P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Estimating the prevalence of borderline personality disorder in psychiatric outpatients using a two-phase procedure</atitle><jtitle>Comprehensive psychiatry</jtitle><addtitle>Compr Psychiatry</addtitle><date>2008-07-01</date><risdate>2008</risdate><volume>49</volume><issue>4</issue><spage>380</spage><epage>386</epage><pages>380-386</pages><issn>0010-440X</issn><eissn>1532-8384</eissn><coden>COPYAV</coden><abstract>Abstract The prevalence of borderline personality disorder (BPD) in outpatient clinics varies greatly (7%-27%) depending on the setting and methodology. We examined the cross-sectional rate of BPD in a general adult outpatient university clinic using a 2-phase procedure: (1) we screened all registered patients with the self-report SCID-II-PQ and (2) we administered the Revised Diagnostic Interview for Borderlines (DIB-R). Sixty-six percent (239/360) of the clinic patients completed the screening: About 72.4% (173/239) (95% confidence interval [CI] = 66.7%, 78.1%) were positive for BPD on the Structured Clinical Interview for DSM-IV Personality Disorders–Patient Questionnaire (SCID-II-PQ), and 22.6% (54/239) (95% CI = 17.3%, 27.9%) were positive for BPD on the DIB-R. Our BPD rate was somewhat higher than recent semistructured interview studies (9%-18%). We believe this is due, in part, to our cross-sectional design and our decision not to exclude acute Axis I disorders. Mostly, however, we believe that our 22.6% incidence of BPD arises from the high morbidity of our sample. Demographic data from 130 of 131 DIB-R completers reveal the following: mean age was 40.2 years, 75.4% were female, most patients were unable to work, and they averaged 3.8 lifetime hospitalizations.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>18555059</pmid><doi>10.1016/j.comppsych.2008.01.007</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0010-440X |
ispartof | Comprehensive psychiatry, 2008-07, Vol.49 (4), p.380-386 |
issn | 0010-440X 1532-8384 |
language | eng |
recordid | cdi_proquest_miscellaneous_69206374 |
source | MEDLINE; Elsevier ScienceDirect Journals Complete |
subjects | Adult Adult and adolescent clinical studies Ambulatory Care Facilities - statistics & numerical data Biological and medical sciences Borderline Personality Disorder - diagnosis Borderline Personality Disorder - epidemiology Borderline Personality Disorder - psychology Clinics Cross-Sectional Studies Disability Evaluation Female Health Surveys Hospitals, University - statistics & numerical data Humans Interview, Psychological Interviews Male Mass Screening Medical sciences Middle Aged Ontario Patient Readmission - statistics & numerical data Personality disorders Personality Inventory - statistics & numerical data Psychiatric Department, Hospital - statistics & numerical data Psychiatry Psychology. Psychoanalysis. Psychiatry Psychometrics - statistics & numerical data Psychopathology. Psychiatry Questionnaires Reproducibility of Results Self destructive behavior Studies Suicides & suicide attempts Therapists |
title | Estimating the prevalence of borderline personality disorder in psychiatric outpatients using a two-phase procedure |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T18%3A30%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Estimating%20the%20prevalence%20of%20borderline%20personality%20disorder%20in%20psychiatric%20outpatients%20using%20a%20two-phase%20procedure&rft.jtitle=Comprehensive%20psychiatry&rft.au=Korzekwa,%20Marilyn%20I&rft.date=2008-07-01&rft.volume=49&rft.issue=4&rft.spage=380&rft.epage=386&rft.pages=380-386&rft.issn=0010-440X&rft.eissn=1532-8384&rft.coden=COPYAV&rft_id=info:doi/10.1016/j.comppsych.2008.01.007&rft_dat=%3Cproquest_cross%3E69206374%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1029886193&rft_id=info:pmid/18555059&rft_els_id=1_s2_0_S0010440X08000278&rfr_iscdi=true |