Dose-dependent Effects of a Glucocorticoid on Prolactin Production

Glucocorticoids are known to stimulate growth hormone (GH) production but to suppress prolactin (PRL) production. However, previous data were obtained with rather high doses of corticosterone. In this study we examined the effects of various doses (10 -12 -10 -7 M) of corticosterone on GH and PRL pr...

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Veröffentlicht in:	ENDOCRINE JOURNAL 2008, Vol.55(2), pp.405-414
Hauptverfasser:	YOKOYAMA, Kotaro, HAYASHI, Mahoko, MOGI, Chihiro, SASAKAWA, Yoshihiro, WATANABE, Gen, TAYA, Kazuyoshi, DEVNATH, Sukumar, INOUE, Kinji
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cell Proliferation - drug effects Corticosterone - pharmacology Dose-Response Relationship, Drug Estradiol - pharmacology Estrogen Glucocorticoid Glucocorticoids - pharmacology Growth Hormone - metabolism Hormone Antagonists - pharmacology Mifepristone - pharmacology Pituitary Pituitary Gland - cytology Pituitary Gland - drug effects Pituitary Gland - metabolism Prolactin Prolactin - metabolism Rats RNA, Messenger - metabolism Somatomammotrope
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