Functional-genomics-based identification of genes that regulate Arabidopsis responses to multiple abiotic stresses
Abiotic stresses are a primary cause of crop loss worldwide. The convergence of stress signalling pathways to a common set of transcription factors suggests the existence of upstream regulatory genes that control plant responses to multiple abiotic stresses. To identify such genes, data from publish...
Gespeichert in:
Veröffentlicht in: | Plant, cell and environment cell and environment, 2008-06, Vol.31 (6), p.697-714 |
---|---|
Hauptverfasser: | , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 714 |
---|---|
container_issue | 6 |
container_start_page | 697 |
container_title | Plant, cell and environment |
container_volume | 31 |
creator | KANT, PRAGYA GORDON, MICHAL KANT, SURYA ZOLLA, GASTON DAVYDOV, OLGA HEIMER, YAIR M CHALIFA-CASPI, VERED SHAKED, RUTH BARAK, SIMON |
description | Abiotic stresses are a primary cause of crop loss worldwide. The convergence of stress signalling pathways to a common set of transcription factors suggests the existence of upstream regulatory genes that control plant responses to multiple abiotic stresses. To identify such genes, data from published Arabidopsis thaliana abiotic stress microarray analyses were combined with our presented global analysis of early heat stress-responsive gene expression, in a relational database. A set of Multiple Stress (MST) genes was identified by scoring each gene for the number of abiotic stresses affecting expression of that gene. ErmineJ over-representation analysis of the MST gene set identified significantly enriched gene ontology biological processes for multiple abiotic stresses and regulatory genes, particularly transcription factors. A subset of MST genes including only regulatory genes that were designated 'Multiple Stress Regulatory' (MSTR) genes, was identified. To validate this strategy for identifying MSTR genes, mutants of the highest-scoring MSTR gene encoding the circadian clock protein CCA1, were tested for altered sensitivity to stress. A double mutant of CCA1 and its structural and functional homolog, LATE ELONGLATED HYPOCOTYL, exhibited greater sensitivity to salt, osmotic and heat stress than wild-type plants. This work provides a reference data set for further study of MSTR genes. |
doi_str_mv | 10.1111/j.1365-3040.2008.01779.x |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69198084</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69198084</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4219-112be46cc640378e038e5bce3e4bdd212b120f500332805e259e7ab4782f2fdb3</originalsourceid><addsrcrecordid>eNqNkMtu1DAUhi1ERacDrwDewC6pL7k4CxbVqKVIlYoEXVuOczJ45MTBTtT27TlhRmVbb2yf_zu3nxDKWc7xXB5yLqsyk6xguWBM5YzXdZM_vSGbF-Et2TBesAwFfk4uUjowhoG6eUfOueJK4GdD4s0y2tmF0fhsD2MYnE1ZaxJ01HUwzq531qw6DT1FABKdf5uZRtgv3sxAr6JpXRem5BIG0xTGtDKBDouf3eSBoh5mZ2maUUfxPTnrjU_w4XRvycPN9a_dbXZ3_-377uous4XgTca5aKGorK0KJmsFTCooWwsSirbrBKpcsL5kTEqhWAmibKA2bVEr0Yu-a-WWfDnWnWL4s0Ca9eCSBe_NCGFJump4o5gqEFRH0MaQUoReT9ENJj5rzvTqtz7o1Va92qpXv_U_v_UTpn489VjaAbr_iSeDEfh8AkyyxvfRjNalF07gao3EHbbk65F7dB6eXz2A_rG7Xl-Y_-mY35ugzT5ij4efOAHWVo3klZR_AR-8pow</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69198084</pqid></control><display><type>article</type><title>Functional-genomics-based identification of genes that regulate Arabidopsis responses to multiple abiotic stresses</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Wiley Free Content</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>KANT, PRAGYA ; GORDON, MICHAL ; KANT, SURYA ; ZOLLA, GASTON ; DAVYDOV, OLGA ; HEIMER, YAIR M ; CHALIFA-CASPI, VERED ; SHAKED, RUTH ; BARAK, SIMON</creator><creatorcontrib>KANT, PRAGYA ; GORDON, MICHAL ; KANT, SURYA ; ZOLLA, GASTON ; DAVYDOV, OLGA ; HEIMER, YAIR M ; CHALIFA-CASPI, VERED ; SHAKED, RUTH ; BARAK, SIMON</creatorcontrib><description>Abiotic stresses are a primary cause of crop loss worldwide. The convergence of stress signalling pathways to a common set of transcription factors suggests the existence of upstream regulatory genes that control plant responses to multiple abiotic stresses. To identify such genes, data from published Arabidopsis thaliana abiotic stress microarray analyses were combined with our presented global analysis of early heat stress-responsive gene expression, in a relational database. A set of Multiple Stress (MST) genes was identified by scoring each gene for the number of abiotic stresses affecting expression of that gene. ErmineJ over-representation analysis of the MST gene set identified significantly enriched gene ontology biological processes for multiple abiotic stresses and regulatory genes, particularly transcription factors. A subset of MST genes including only regulatory genes that were designated 'Multiple Stress Regulatory' (MSTR) genes, was identified. To validate this strategy for identifying MSTR genes, mutants of the highest-scoring MSTR gene encoding the circadian clock protein CCA1, were tested for altered sensitivity to stress. A double mutant of CCA1 and its structural and functional homolog, LATE ELONGLATED HYPOCOTYL, exhibited greater sensitivity to salt, osmotic and heat stress than wild-type plants. This work provides a reference data set for further study of MSTR genes.</description><identifier>ISSN: 0140-7791</identifier><identifier>EISSN: 1365-3040</identifier><identifier>DOI: 10.1111/j.1365-3040.2008.01779.x</identifier><identifier>PMID: 18182014</identifier><identifier>CODEN: PLCEDV</identifier><language>eng</language><publisher>Oxford, UK: Oxford, UK : Blackwell Publishing Ltd</publisher><subject>abiotic stress responses ; Arabidopsis - genetics ; Arabidopsis - metabolism ; Arabidopsis Proteins - genetics ; Arabidopsis Proteins - metabolism ; Arabidopsis thaliana ; Biological and medical sciences ; DNA, Plant - genetics ; Fundamental and applied biological sciences. Psychology ; Gene Expression Profiling ; Gene Expression Regulation, Plant - physiology ; Genes, Plant ; Genes. Genome ; Genome, Plant ; Genomics ; heat stress transcriptome ; Molecular and cellular biology ; Molecular genetics ; multiple stress genes ; Mutation ; Oligonucleotide Array Sequence Analysis ; Signal Transduction - physiology ; Sodium Chloride ; Water</subject><ispartof>Plant, cell and environment, 2008-06, Vol.31 (6), p.697-714</ispartof><rights>2008 The Authors. Journal compilation © 2008 Blackwell Publishing Ltd</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4219-112be46cc640378e038e5bce3e4bdd212b120f500332805e259e7ab4782f2fdb3</citedby><cites>FETCH-LOGICAL-c4219-112be46cc640378e038e5bce3e4bdd212b120f500332805e259e7ab4782f2fdb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-3040.2008.01779.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-3040.2008.01779.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,1428,27905,27906,45555,45556,46390,46814</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20379300$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18182014$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KANT, PRAGYA</creatorcontrib><creatorcontrib>GORDON, MICHAL</creatorcontrib><creatorcontrib>KANT, SURYA</creatorcontrib><creatorcontrib>ZOLLA, GASTON</creatorcontrib><creatorcontrib>DAVYDOV, OLGA</creatorcontrib><creatorcontrib>HEIMER, YAIR M</creatorcontrib><creatorcontrib>CHALIFA-CASPI, VERED</creatorcontrib><creatorcontrib>SHAKED, RUTH</creatorcontrib><creatorcontrib>BARAK, SIMON</creatorcontrib><title>Functional-genomics-based identification of genes that regulate Arabidopsis responses to multiple abiotic stresses</title><title>Plant, cell and environment</title><addtitle>Plant Cell Environ</addtitle><description>Abiotic stresses are a primary cause of crop loss worldwide. The convergence of stress signalling pathways to a common set of transcription factors suggests the existence of upstream regulatory genes that control plant responses to multiple abiotic stresses. To identify such genes, data from published Arabidopsis thaliana abiotic stress microarray analyses were combined with our presented global analysis of early heat stress-responsive gene expression, in a relational database. A set of Multiple Stress (MST) genes was identified by scoring each gene for the number of abiotic stresses affecting expression of that gene. ErmineJ over-representation analysis of the MST gene set identified significantly enriched gene ontology biological processes for multiple abiotic stresses and regulatory genes, particularly transcription factors. A subset of MST genes including only regulatory genes that were designated 'Multiple Stress Regulatory' (MSTR) genes, was identified. To validate this strategy for identifying MSTR genes, mutants of the highest-scoring MSTR gene encoding the circadian clock protein CCA1, were tested for altered sensitivity to stress. A double mutant of CCA1 and its structural and functional homolog, LATE ELONGLATED HYPOCOTYL, exhibited greater sensitivity to salt, osmotic and heat stress than wild-type plants. This work provides a reference data set for further study of MSTR genes.</description><subject>abiotic stress responses</subject><subject>Arabidopsis - genetics</subject><subject>Arabidopsis - metabolism</subject><subject>Arabidopsis Proteins - genetics</subject><subject>Arabidopsis Proteins - metabolism</subject><subject>Arabidopsis thaliana</subject><subject>Biological and medical sciences</subject><subject>DNA, Plant - genetics</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gene Expression Profiling</subject><subject>Gene Expression Regulation, Plant - physiology</subject><subject>Genes, Plant</subject><subject>Genes. Genome</subject><subject>Genome, Plant</subject><subject>Genomics</subject><subject>heat stress transcriptome</subject><subject>Molecular and cellular biology</subject><subject>Molecular genetics</subject><subject>multiple stress genes</subject><subject>Mutation</subject><subject>Oligonucleotide Array Sequence Analysis</subject><subject>Signal Transduction - physiology</subject><subject>Sodium Chloride</subject><subject>Water</subject><issn>0140-7791</issn><issn>1365-3040</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMtu1DAUhi1ERacDrwDewC6pL7k4CxbVqKVIlYoEXVuOczJ45MTBTtT27TlhRmVbb2yf_zu3nxDKWc7xXB5yLqsyk6xguWBM5YzXdZM_vSGbF-Et2TBesAwFfk4uUjowhoG6eUfOueJK4GdD4s0y2tmF0fhsD2MYnE1ZaxJ01HUwzq531qw6DT1FABKdf5uZRtgv3sxAr6JpXRem5BIG0xTGtDKBDouf3eSBoh5mZ2maUUfxPTnrjU_w4XRvycPN9a_dbXZ3_-377uous4XgTca5aKGorK0KJmsFTCooWwsSirbrBKpcsL5kTEqhWAmibKA2bVEr0Yu-a-WWfDnWnWL4s0Ca9eCSBe_NCGFJump4o5gqEFRH0MaQUoReT9ENJj5rzvTqtz7o1Va92qpXv_U_v_UTpn489VjaAbr_iSeDEfh8AkyyxvfRjNalF07gao3EHbbk65F7dB6eXz2A_rG7Xl-Y_-mY35ugzT5ij4efOAHWVo3klZR_AR-8pow</recordid><startdate>200806</startdate><enddate>200806</enddate><creator>KANT, PRAGYA</creator><creator>GORDON, MICHAL</creator><creator>KANT, SURYA</creator><creator>ZOLLA, GASTON</creator><creator>DAVYDOV, OLGA</creator><creator>HEIMER, YAIR M</creator><creator>CHALIFA-CASPI, VERED</creator><creator>SHAKED, RUTH</creator><creator>BARAK, SIMON</creator><general>Oxford, UK : Blackwell Publishing Ltd</general><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200806</creationdate><title>Functional-genomics-based identification of genes that regulate Arabidopsis responses to multiple abiotic stresses</title><author>KANT, PRAGYA ; GORDON, MICHAL ; KANT, SURYA ; ZOLLA, GASTON ; DAVYDOV, OLGA ; HEIMER, YAIR M ; CHALIFA-CASPI, VERED ; SHAKED, RUTH ; BARAK, SIMON</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4219-112be46cc640378e038e5bce3e4bdd212b120f500332805e259e7ab4782f2fdb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>abiotic stress responses</topic><topic>Arabidopsis - genetics</topic><topic>Arabidopsis - metabolism</topic><topic>Arabidopsis Proteins - genetics</topic><topic>Arabidopsis Proteins - metabolism</topic><topic>Arabidopsis thaliana</topic><topic>Biological and medical sciences</topic><topic>DNA, Plant - genetics</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gene Expression Profiling</topic><topic>Gene Expression Regulation, Plant - physiology</topic><topic>Genes, Plant</topic><topic>Genes. Genome</topic><topic>Genome, Plant</topic><topic>Genomics</topic><topic>heat stress transcriptome</topic><topic>Molecular and cellular biology</topic><topic>Molecular genetics</topic><topic>multiple stress genes</topic><topic>Mutation</topic><topic>Oligonucleotide Array Sequence Analysis</topic><topic>Signal Transduction - physiology</topic><topic>Sodium Chloride</topic><topic>Water</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KANT, PRAGYA</creatorcontrib><creatorcontrib>GORDON, MICHAL</creatorcontrib><creatorcontrib>KANT, SURYA</creatorcontrib><creatorcontrib>ZOLLA, GASTON</creatorcontrib><creatorcontrib>DAVYDOV, OLGA</creatorcontrib><creatorcontrib>HEIMER, YAIR M</creatorcontrib><creatorcontrib>CHALIFA-CASPI, VERED</creatorcontrib><creatorcontrib>SHAKED, RUTH</creatorcontrib><creatorcontrib>BARAK, SIMON</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Plant, cell and environment</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KANT, PRAGYA</au><au>GORDON, MICHAL</au><au>KANT, SURYA</au><au>ZOLLA, GASTON</au><au>DAVYDOV, OLGA</au><au>HEIMER, YAIR M</au><au>CHALIFA-CASPI, VERED</au><au>SHAKED, RUTH</au><au>BARAK, SIMON</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Functional-genomics-based identification of genes that regulate Arabidopsis responses to multiple abiotic stresses</atitle><jtitle>Plant, cell and environment</jtitle><addtitle>Plant Cell Environ</addtitle><date>2008-06</date><risdate>2008</risdate><volume>31</volume><issue>6</issue><spage>697</spage><epage>714</epage><pages>697-714</pages><issn>0140-7791</issn><eissn>1365-3040</eissn><coden>PLCEDV</coden><abstract>Abiotic stresses are a primary cause of crop loss worldwide. The convergence of stress signalling pathways to a common set of transcription factors suggests the existence of upstream regulatory genes that control plant responses to multiple abiotic stresses. To identify such genes, data from published Arabidopsis thaliana abiotic stress microarray analyses were combined with our presented global analysis of early heat stress-responsive gene expression, in a relational database. A set of Multiple Stress (MST) genes was identified by scoring each gene for the number of abiotic stresses affecting expression of that gene. ErmineJ over-representation analysis of the MST gene set identified significantly enriched gene ontology biological processes for multiple abiotic stresses and regulatory genes, particularly transcription factors. A subset of MST genes including only regulatory genes that were designated 'Multiple Stress Regulatory' (MSTR) genes, was identified. To validate this strategy for identifying MSTR genes, mutants of the highest-scoring MSTR gene encoding the circadian clock protein CCA1, were tested for altered sensitivity to stress. A double mutant of CCA1 and its structural and functional homolog, LATE ELONGLATED HYPOCOTYL, exhibited greater sensitivity to salt, osmotic and heat stress than wild-type plants. This work provides a reference data set for further study of MSTR genes.</abstract><cop>Oxford, UK</cop><pub>Oxford, UK : Blackwell Publishing Ltd</pub><pmid>18182014</pmid><doi>10.1111/j.1365-3040.2008.01779.x</doi><tpages>18</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0140-7791 |
ispartof | Plant, cell and environment, 2008-06, Vol.31 (6), p.697-714 |
issn | 0140-7791 1365-3040 |
language | eng |
recordid | cdi_proquest_miscellaneous_69198084 |
source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Wiley Free Content; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | abiotic stress responses Arabidopsis - genetics Arabidopsis - metabolism Arabidopsis Proteins - genetics Arabidopsis Proteins - metabolism Arabidopsis thaliana Biological and medical sciences DNA, Plant - genetics Fundamental and applied biological sciences. Psychology Gene Expression Profiling Gene Expression Regulation, Plant - physiology Genes, Plant Genes. Genome Genome, Plant Genomics heat stress transcriptome Molecular and cellular biology Molecular genetics multiple stress genes Mutation Oligonucleotide Array Sequence Analysis Signal Transduction - physiology Sodium Chloride Water |
title | Functional-genomics-based identification of genes that regulate Arabidopsis responses to multiple abiotic stresses |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T23%3A03%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Functional-genomics-based%20identification%20of%20genes%20that%20regulate%20Arabidopsis%20responses%20to%20multiple%20abiotic%20stresses&rft.jtitle=Plant,%20cell%20and%20environment&rft.au=KANT,%20PRAGYA&rft.date=2008-06&rft.volume=31&rft.issue=6&rft.spage=697&rft.epage=714&rft.pages=697-714&rft.issn=0140-7791&rft.eissn=1365-3040&rft.coden=PLCEDV&rft_id=info:doi/10.1111/j.1365-3040.2008.01779.x&rft_dat=%3Cproquest_cross%3E69198084%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=69198084&rft_id=info:pmid/18182014&rfr_iscdi=true |