Metabolism of remifentanil during liver transplantation

We have investigated the pharmacokinetics of remifentanil and its less potent metabolite, GR90291, in six adult patients undergoing orthotopic liver transplantation (OLT). A single bolus infusion of remifentanil 10 micrograms kg-1 min-1 was given at the beginning of the dissection and anhepatic phas...

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Veröffentlicht in:	British journal of anaesthesia : BJA 1998-12, Vol.81 (6), p.881-886
Hauptverfasser:	Navapurkar, V U, Archer, S, Gupta, S K, Muir, K T, Frazer, N, Park, G R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Analgesics Analgesics, Opioid - blood Analgesics, Opioid - pharmacokinetics Biological and medical sciences Female Half-Life Humans Intraoperative Care Liver Transplantation Lung - metabolism Male Medical sciences Middle Aged Neuropharmacology Pharmacology. Drug treatments Piperidines - blood Piperidines - pharmacokinetics Remifentanil
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