Berberine Induced Down-regulation of Matrix Metalloproteinase-1, -2 and -9 in Human Gastric Cancer Cells (SNU-5) In Vitro

Berberine, a yellow benzylisoquinoline alkaloid, is a constituent of Coptis chines and is commonly used in Chinese herbal medicine for patients with gastrointestinal disorders. The pharmacological effects of berberine include anti-inflammation, antidiarrhetic, antimalarial, and even antimicrobial ac...

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Veröffentlicht in:	In vivo (Athens) 2008-03, Vol.22 (2), p.223-230
Hauptverfasser:	Lin, Jing-Pin, Yang, Jai-Sing, Wu, Chih-Chung, Lin, Song-Shei, Hsieh, Wen-Tsong, Lin, Meng-Liang, Yu, Fu-Shun, Yu, Chun-Shu, Chen, Guang-Wei, Chang, Yung-Hsien, Chung, Jing-Gung
Format:	Artikel
Sprache:	eng
Schlagworte:	Berberine - pharmacology Cell Line, Tumor Cell Survival - drug effects Dose-Response Relationship, Drug Down-Regulation Gene Expression Regulation, Enzymologic Gene Expression Regulation, Neoplastic Humans In Vitro Techniques Matrix Metalloproteinase 1 - metabolism Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - metabolism RNA, Messenger - metabolism Statistics as Topic Stomach Neoplasms - drug therapy Stomach Neoplasms - pathology
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