Septic arthritis of hip after radiotherapy for carcinoma of cervix
Radiation-induced damage to the bone is characterised by four main pathological findings: osteoporosis, bone-marrow fibrosis, trabecular microfractures and disseminated areas of focal necrosis. The complications of radiotherapy affecting hip and pelvis are well known, but septic arthritis of the hip...
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Veröffentlicht in: | Singapore medical journal 2008-05, Vol.49 (5), p.e142-e144 |
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description | Radiation-induced damage to the bone is characterised by four main pathological findings: osteoporosis, bone-marrow fibrosis, trabecular microfractures and disseminated areas of focal necrosis. The complications of radiotherapy affecting hip and pelvis are well known, but septic arthritis of the hip joint following pelvic irradiation is a rare occurrence. Radiation-induced damage associated with a compromised host defence may be considered responsible for this complication. We report septic arthritis of hip joint in a 64-year-old woman who was treated with pelvic radiotherapy for carcinoma of the cervix eight years ago. She was successfully treated by two-stage reconstruction, consisting of debridement and antibiotic-loaded cement spacer insertion in the first stage and total hip replacement in the second stage. |
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The complications of radiotherapy affecting hip and pelvis are well known, but septic arthritis of the hip joint following pelvic irradiation is a rare occurrence. Radiation-induced damage associated with a compromised host defence may be considered responsible for this complication. We report septic arthritis of hip joint in a 64-year-old woman who was treated with pelvic radiotherapy for carcinoma of the cervix eight years ago. She was successfully treated by two-stage reconstruction, consisting of debridement and antibiotic-loaded cement spacer insertion in the first stage and total hip replacement in the second stage.</description><identifier>ISSN: 0037-5675</identifier><identifier>PMID: 18465041</identifier><language>eng</language><publisher>Singapore</publisher><subject>Arthritis, Infectious - diagnosis ; Carcinoma - radiotherapy ; Female ; Hip Joint - microbiology ; Humans ; Immunocompromised Host ; Middle Aged ; Opportunistic Infections - diagnosis ; Streptococcal Infections - diagnosis ; Uterine Cervical Neoplasms - radiotherapy</subject><ispartof>Singapore medical journal, 2008-05, Vol.49 (5), p.e142-e144</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18465041$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Diwanji, S R</creatorcontrib><creatorcontrib>Cho, S G</creatorcontrib><creatorcontrib>Seon, J K</creatorcontrib><creatorcontrib>Yoon, T R</creatorcontrib><title>Septic arthritis of hip after radiotherapy for carcinoma of cervix</title><title>Singapore medical journal</title><addtitle>Singapore Med J</addtitle><description>Radiation-induced damage to the bone is characterised by four main pathological findings: osteoporosis, bone-marrow fibrosis, trabecular microfractures and disseminated areas of focal necrosis. The complications of radiotherapy affecting hip and pelvis are well known, but septic arthritis of the hip joint following pelvic irradiation is a rare occurrence. Radiation-induced damage associated with a compromised host defence may be considered responsible for this complication. We report septic arthritis of hip joint in a 64-year-old woman who was treated with pelvic radiotherapy for carcinoma of the cervix eight years ago. She was successfully treated by two-stage reconstruction, consisting of debridement and antibiotic-loaded cement spacer insertion in the first stage and total hip replacement in the second stage.</description><subject>Arthritis, Infectious - diagnosis</subject><subject>Carcinoma - radiotherapy</subject><subject>Female</subject><subject>Hip Joint - microbiology</subject><subject>Humans</subject><subject>Immunocompromised Host</subject><subject>Middle Aged</subject><subject>Opportunistic Infections - diagnosis</subject><subject>Streptococcal Infections - diagnosis</subject><subject>Uterine Cervical Neoplasms - radiotherapy</subject><issn>0037-5675</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1z7tOwzAYBWAPIFoKr4A8sUXyNY5HqLhUqsQAzNEfXxSjpDa2i-jbU0SZzvLp6JwztCSEq0a2Si7QZSkfhDBFuu4CLWgnWkkEXaL7V5dqMBhyHXOooeDo8RgSBl9dxhlsiHV0GdIB-5ixgWzCLs7w64zLX-H7Cp17mIq7PuUKvT8-vK2fm-3L02Z9t20SI7o2XhGgYDUzrSdglTXSCQGCces5Yd4PjBsYBmI00x6AH8dK3lEyaDEwJfkK3f71phw_967Ufg7FuGmCnYv70reaasEoPcKbE9wPs7N9ymGGfOj_X_MfvRZS1w</recordid><startdate>200805</startdate><enddate>200805</enddate><creator>Diwanji, S R</creator><creator>Cho, S G</creator><creator>Seon, J K</creator><creator>Yoon, T R</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200805</creationdate><title>Septic arthritis of hip after radiotherapy for carcinoma of cervix</title><author>Diwanji, S R ; Cho, S G ; Seon, J K ; Yoon, T R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p209t-f70a1ad92c6f0ad7dc5e44a423df302ffb23cabb0c929faa327053810b94b2753</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Arthritis, Infectious - diagnosis</topic><topic>Carcinoma - radiotherapy</topic><topic>Female</topic><topic>Hip Joint - microbiology</topic><topic>Humans</topic><topic>Immunocompromised Host</topic><topic>Middle Aged</topic><topic>Opportunistic Infections - diagnosis</topic><topic>Streptococcal Infections - diagnosis</topic><topic>Uterine Cervical Neoplasms - radiotherapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Diwanji, S R</creatorcontrib><creatorcontrib>Cho, S G</creatorcontrib><creatorcontrib>Seon, J K</creatorcontrib><creatorcontrib>Yoon, T R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Singapore medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Diwanji, S R</au><au>Cho, S G</au><au>Seon, J K</au><au>Yoon, T R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Septic arthritis of hip after radiotherapy for carcinoma of cervix</atitle><jtitle>Singapore medical journal</jtitle><addtitle>Singapore Med J</addtitle><date>2008-05</date><risdate>2008</risdate><volume>49</volume><issue>5</issue><spage>e142</spage><epage>e144</epage><pages>e142-e144</pages><issn>0037-5675</issn><abstract>Radiation-induced damage to the bone is characterised by four main pathological findings: osteoporosis, bone-marrow fibrosis, trabecular microfractures and disseminated areas of focal necrosis. The complications of radiotherapy affecting hip and pelvis are well known, but septic arthritis of the hip joint following pelvic irradiation is a rare occurrence. Radiation-induced damage associated with a compromised host defence may be considered responsible for this complication. We report septic arthritis of hip joint in a 64-year-old woman who was treated with pelvic radiotherapy for carcinoma of the cervix eight years ago. She was successfully treated by two-stage reconstruction, consisting of debridement and antibiotic-loaded cement spacer insertion in the first stage and total hip replacement in the second stage.</abstract><cop>Singapore</cop><pmid>18465041</pmid></addata></record> |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
subjects | Arthritis, Infectious - diagnosis Carcinoma - radiotherapy Female Hip Joint - microbiology Humans Immunocompromised Host Middle Aged Opportunistic Infections - diagnosis Streptococcal Infections - diagnosis Uterine Cervical Neoplasms - radiotherapy |
title | Septic arthritis of hip after radiotherapy for carcinoma of cervix |
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