Stromal gene expression predicts clinical outcome in breast cancer

Although it is increasingly evident that cancer is influenced by signals emanating from tumor stroma, little is known regarding how changes in stromal gene expression affect epithelial tumor progression. We used laser capture microdissection to compare gene expression profiles of tumor stroma from 5...

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Veröffentlicht in:	Nature medicine 2008-05, Vol.14 (5), p.518-527
Hauptverfasser:	Park, Morag, Chen, Haiying, Sadekova, Svetlana, Zhao, Hong, Pepin, Francois, Souleimanova, Margarita, Omeroglu, Atilla, Bertos, Nicholas, Finak, Greg, Omeroglu, Gulbeyaz, Hallett, Michael, Meterissian, Sarkis
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Biomedicine Breast cancer Breast Neoplasms - genetics Breast Neoplasms - metabolism Cancer Cancer Research Clinical outcomes Development and progression Female Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Genes Genetic aspects Genetic Markers - genetics Humans Hypoxia Infectious Diseases Lasers Medical prognosis Metabolic Diseases Microdissection - methods Molecular Medicine Neurosciences Oligonucleotide Array Sequence Analysis Oncology Patient outcomes Prognosis Regression Analysis Stromal Cells - metabolism Tumors
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