The synthesis of sub-micron magnetic particles and their use for preparative purification of proteins

A novel one‐step protocol for the preparation of sub‐micron magnetic particles as small as 30 nm in diameter has been developed. The surface of the particles was functionalized with carboxyl groups (∼1 COOH per 15Å2) to facilitate the attachment of affinity ligands. The high surface area of the resu...

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Veröffentlicht in:Biotechnology and bioengineering 1998-11, Vol.60 (4), p.419-424
Hauptverfasser: Khng, Hwee Peng, Cunliffe, David, Davies, Stephen, Turner, Nigel A., Vulfson, Evgeny N.
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Sprache:eng
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