Intrinsic optical signals in vitro: a tool to measure alterations in extracellular space with two-dimensional resolution

In excitable tissues, extensive neuronal activity or pathophysiological conditions, such as spreading depression, ischemic infarct, or epileptic seizure, are accompanied by changes in extracellular space volume. Extracellular space volume, in turn, influences neuronal excitability and extracellular...

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Veröffentlicht in:	Brain research bulletin 1998-12, Vol.47 (6), p.649-655
Hauptverfasser:	Holthoff, K, Witte, O.W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain slice Cerebral Cortex - cytology Cerebral Cortex - physiology Extracellular Space - physiology Extracellular space volume Fundamental and applied biological sciences. Psychology General aspects. Models. Methods Image Processing, Computer-Assisted - instrumentation Image Processing, Computer-Assisted - methods Intrinsic optical signals Male Microelectrodes Neurons - physiology Optics and Photonics Organ Culture Techniques Potassium Potassium - physiology Rat Rats Rats, Wistar Vertebrates: nervous system and sense organs
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