Prorenin and (pro)renin receptor: a review of available data from in vitro studies and experimental models in rodents

The discovery of a (pro)renin receptor [(P)RR] and the introduction of renin inhibitors in the clinic have brought renin and prorenin back into the spotlight. The (P)RR binds both renin and its inactive precursor prorenin, and such binding triggers intracellular signalling that upregulates the expre...

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Veröffentlicht in:	Experimental physiology 2008-05, Vol.93 (5), p.557-563
Hauptverfasser:	Nguyen, Geneviève, Danser, A. H. Jan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Animals Cardiovascular Diseases - metabolism Kidney Diseases - metabolism Mice Rats Receptors, Cell Surface - metabolism Receptors, Cell Surface - physiology Renin - metabolism Renin - physiology
Online-Zugang:	Volltext
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