Different cytokines modulate ubiquitin gene expression in rat skeletal muscle

Intravenous administration of different cytokines caused important changes in the expression of ubiquitin genes in skeletal muscle. Tumour necrosis factor- α caused a 2.2- and 1.9-fold increase in the expression of the 2.4 and 1.2 kb transcripts, respectively. Administration of interferon- γ also ca...

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Veröffentlicht in:	Cancer letters 1998-11, Vol.133 (1), p.83-87
Hauptverfasser:	Llovera, Marta, Carbó, Neus, López-Soriano, Joaquı́n, Garcı́a-Martı́nez, Cèlia, Busquets, Sı́lvia, Alvarez, Belén, Agell, Neus, Costelli, Paola, López-Soriano, Francisco J., Celada, Antonio, Argilés, Josep M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Cachexia - metabolism Cancer cachexia Cytokines - pharmacology Gene Expression Regulation - drug effects IFN- γ IL-1 IL-6 Immunotherapy Interferon-gamma - pharmacology Interleukin-1 - pharmacology Interleukin-6 - pharmacology LIF Male Medical sciences Muscle waste Muscle, Skeletal - metabolism Pharmacology. Drug treatments Rats Rats, Wistar TNF- α Tumor Necrosis Factor-alpha - pharmacology Ubiquitins - genetics
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