Treatment of obstructive sleep apnoea leads to enhanced pulmonary vascular nitric oxide release

Abstract Background Obstructive sleep apnoea (OSA) is associated with pulmonary hypertension, however neither the pathogenesis of pulmonary vascular disease nor the effect of successful treatment of OSA on pulmonary vascular physiology has been characterised. Methods Seven subjects aged 52 (range 36...

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Veröffentlicht in:	International journal of cardiology 2008-05, Vol.126 (2), p.229-233
Hauptverfasser:	Lattimore, Jo-Dee L, Wilcox, Ian, Adams, Mark R, Kilian, Jens G, Celermajer, David S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Blood Flow Velocity - physiology Cardiology. Vascular system Cardiovascular Continuous Positive Airway Pressure - methods Continuous positive airways pressure Humans Lung - blood supply Lung - metabolism Lung - secretion Male Medical sciences Microcirculation - metabolism Microcirculation - secretion Middle Aged Nitric oxide Nitric Oxide - biosynthesis Nitric Oxide - secretion Pneumology Pulmonary Circulation - physiology Pulmonary hypertension Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases Respiratory system : syndromes and miscellaneous diseases Sleep Apnea, Obstructive - metabolism Sleep Apnea, Obstructive - physiopathology Sleep Apnea, Obstructive - therapy
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