CPG 7909 Adjuvant plus Hepatitis B Virus Vaccination in HIV-Infected Adults Achieves Long-Term Seroprotection for Up to 5 Years

Background. Human immunodeficiency virus (HIV)–infected persons are hyporesponsive to hepatitis B virus (HBV) vaccination. CPG 7909 is an oligodeoxynucleotide containing immunostimulatory CpG motifs that activate human B and plasmacytoid dendritic cells via Toll-like receptor 9. We previously report...

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Veröffentlicht in:	Clinical infectious diseases 2008-04, Vol.46 (8), p.1310-1314
Hauptverfasser:	Cooper, C. L., Angel, J. B., Seguin, I., Davis, H. L., Cameron, D. W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Adults Antibodies Biological and medical sciences Dosage Double-Blind Method Female Geometric mean Hepatitis Hepatitis B Hepatitis B Vaccines - administration & dosage Hepatitis B Vaccines - immunology Hepatitis B virus Hepatology HIV HIV Infections - immunology HIV Infections - prevention & control HIV/AIDS Human immunodeficiency virus Human viral diseases Humans Immunization Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infections Infectious diseases Liver Male Medical sciences Middle Aged Oligodeoxyribonucleotides - administration & dosage Oligodeoxyribonucleotides - immunology Pharmaceutical preparations Surface antigens Time Factors Treatment Outcome Vaccination Vaccination - methods Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral hepatitis
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