Genetic Variations and Haplotypes of ABCC2 Encoding MRP2 in a Japanese Population

The multidrug resistance-associated protein 2 (MRP2) encoded by the ABCC2 gene is expressed in the liver, intestine and kidneys and preferentially exports organic anions or conjugates with glucuronide or glutathione. In this study, all 32 exons and the 5′-flanking region of ABCC2 in 236 Japanese wer...

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Veröffentlicht in:	DRUG METABOLISM AND PHARMACOKINETICS 2008-01, Vol.23 (2), p.139-147
Hauptverfasser:	Sai, Kimie, Saito, Yoshiro, Itoda, Masaya, Fukushima-Uesaka, Hiromi, Nishimaki-Mogami, Tomoko, Ozawa, Shogo, Maekawa, Keiko, Kurose, Kouichi, Kaniwa, Nahoko, Kawamoto, Manabu, Kamatani, Naoyuki, Shirao, Kuniaki, Hamaguchi, Tetsuya, Yamamoto, Noboru, Kunitoh, Hideo, Ohe, Yuichiro, Yamada, Yasuhide, Tamura, Tomohide, Yoshida, Teruhiko, Minami, Hironobu, Matsumura, Yasuhiro, Ohtsu, Atsushi, Saijo, Nagahiro, Sawada, Jun-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	ABCC2 amino acid change Asian Continental Ancestry Group European Continental Ancestry Group Genetic Variation haplotype Haplotypes Humans Membrane Transport Proteins - genetics MRP2 Multidrug Resistance-Associated Proteins - genetics Polymorphism, Single Nucleotide
Online-Zugang:	Volltext
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