SERS--a single-molecule and nanoscale tool for bioanalytics
Surface enhanced Raman scattering (SERS) at extremely high enhancement level turns the weak inelastic scattering effect of photons on vibrational quantum states into a structurally sensitive single-molecule and nanoscale probe. The effect opens up exciting opportunities for applications of vibration...
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Veröffentlicht in: | Chemical Society reviews 2008-05, Vol.37 (5), p.1052-1060 |
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creator | Kneipp, Janina Kneipp, Harald Kneipp, Katrin |
description | Surface enhanced Raman scattering (SERS) at extremely high enhancement level turns the weak inelastic scattering effect of photons on vibrational quantum states into a structurally sensitive single-molecule and nanoscale probe. The effect opens up exciting opportunities for applications of vibrational spectroscopy in biology. The concept of SERS can be extended to two-photon excitation by exploiting surface enhanced hyper-Raman scattering (SEHRS). This critical review introduces the physics behind single-molecule SERS and discusses the capabilities of the effect in bioanalytics (100 references). |
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source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
subjects | Animals Cells - chemistry Fluorescent Dyes - chemistry Gold - chemistry Humans Metal Nanoparticles Molecular Probes - chemistry Silver - chemistry Spectrum Analysis, Raman - methods |
title | SERS--a single-molecule and nanoscale tool for bioanalytics |
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