Atrial fibrillation as a nonpsychiatric predictor of delirium after cardiac surgery: a pilot study

Preoperative atrial fibrillation (AF) increases the risk of cardiac surgery and the occurrence of postoperative complications, including arrhythmias, low-output syndrome, delirium, and death. The aim was to evaluate its direct influence on prognosis of patients subjected to cardiac surgery. This is...

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Veröffentlicht in:Medical science monitor 2008-05, Vol.14 (5), p.CR286-CR291
Hauptverfasser: Banach, Maciej, Kazmierski, Jakub, Kowman, Maciej, Okonski, Piotr K, Sobow, Tomasz, Kloszewska, Iwona, Mikhailidis, Dimitri P, Goch, Aleksander, Banys, Andrzej, Rysz, Jacek, Goch, Jan Henryk, Jaszewski, Ryszard
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container_end_page CR291
container_issue 5
container_start_page CR286
container_title Medical science monitor
container_volume 14
creator Banach, Maciej
Kazmierski, Jakub
Kowman, Maciej
Okonski, Piotr K
Sobow, Tomasz
Kloszewska, Iwona
Mikhailidis, Dimitri P
Goch, Aleksander
Banys, Andrzej
Rysz, Jacek
Goch, Jan Henryk
Jaszewski, Ryszard
description Preoperative atrial fibrillation (AF) increases the risk of cardiac surgery and the occurrence of postoperative complications, including arrhythmias, low-output syndrome, delirium, and death. The aim was to evaluate its direct influence on prognosis of patients subjected to cardiac surgery. This is a pilot study of the CODACS trial (COnsciousness Disorders After Cardiac Surgery). Two hundred sixty patients admitted for open-heart surgery were prospectively included in the study. Preoperative AF was diagnosed on the basis of multiple electrocardiographic examinations and confirmed by 24-h Holter monitoring. Diagnosis of delirium following surgical intervention was based on DSM-IV criteria. Preoperative AF was diagnosed in 23 patients (8.8%): in 15 patients in the nondelirious group (7%) and 8 (27.0%) in the delirious group. Preoperative AF was an independent predictor of postoperative delirium (p
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The aim was to evaluate its direct influence on prognosis of patients subjected to cardiac surgery. This is a pilot study of the CODACS trial (COnsciousness Disorders After Cardiac Surgery). Two hundred sixty patients admitted for open-heart surgery were prospectively included in the study. Preoperative AF was diagnosed on the basis of multiple electrocardiographic examinations and confirmed by 24-h Holter monitoring. Diagnosis of delirium following surgical intervention was based on DSM-IV criteria. Preoperative AF was diagnosed in 23 patients (8.8%): in 15 patients in the nondelirious group (7%) and 8 (27.0%) in the delirious group. Preoperative AF was an independent predictor of postoperative delirium (p&lt;0.001), increasing its risk of occurrence over sevenfold (OR=7.2). AF also increased the risk of such postoperative complications as supraventricular arrhythmia (AF: 78.3% vs. non-AF: 22.8%, p&lt;0.001), stroke (8.7% vs. 1.3%, p&lt;0.001), and low-output syndrome (21.7% vs. 17.3%, p=0.033) and worsened prognosis, significantly increasing the risk of death (8.7% vs. 0.8%, p&lt;0.001). Preoperative AF was an independent risk factor of postoperative delirium (OR=7.2). It was also associated with significantly worse postoperative outcome (supraventricular arrhythmia, stroke, low-output syndrome, and risk of death). These results and data from available studies suggest that preoperative AF should be considered as an important predictor of postoperative outcome. 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The aim was to evaluate its direct influence on prognosis of patients subjected to cardiac surgery. This is a pilot study of the CODACS trial (COnsciousness Disorders After Cardiac Surgery). Two hundred sixty patients admitted for open-heart surgery were prospectively included in the study. Preoperative AF was diagnosed on the basis of multiple electrocardiographic examinations and confirmed by 24-h Holter monitoring. Diagnosis of delirium following surgical intervention was based on DSM-IV criteria. Preoperative AF was diagnosed in 23 patients (8.8%): in 15 patients in the nondelirious group (7%) and 8 (27.0%) in the delirious group. Preoperative AF was an independent predictor of postoperative delirium (p&lt;0.001), increasing its risk of occurrence over sevenfold (OR=7.2). 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subjects Aged
Atrial Fibrillation - diagnosis
Delirium - diagnosis
Electrocardiography
Female
Humans
Male
Middle Aged
Pilot Projects
Postoperative Complications
Prognosis
Risk Factors
Thoracic Surgery - methods
Treatment Outcome
title Atrial fibrillation as a nonpsychiatric predictor of delirium after cardiac surgery: a pilot study
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