Allelic Diversity in the Merozoite Surface Protein-1 and Epidemiology of Multiple-Clone Plasmodium falciparum Infections in Northern Tanzania

Allelic diversity in the merozoite surface protein-1 (MSP-1) of Plasmodium falciparum, a major malaria vaccine candidate, was examined in clinical isolates from holoendemic northern Tanzania. The variable blocks 2, 4a, 4b, 6, and 10 of the MSP-1 gene were typed by allelic type-specific polymerase ch...

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