Treated plasma cell lesions of bone with MRI signs of response to treatment : unexpected pathological findings

Two cases of treated plasma cell lesions of bone are reported for which contrast-enhanced MRI had suggested necrosis, based on lack of enhancement after gadolinium injection, and in which pathologic examinations revealed the presence of extensive viable neoplastic tissue. These cases highlight the n...

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Veröffentlicht in:Skeletal radiology 1998-12, Vol.27 (12), p.692-695
Hauptverfasser: LECOUVET, F. E, DE NAYER, P, GARBAR, C, NOËL, H, MALGHEM, J, MALDAGUE, B. E, VANDE BERG, B. C
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container_end_page 695
container_issue 12
container_start_page 692
container_title Skeletal radiology
container_volume 27
creator LECOUVET, F. E
DE NAYER, P
GARBAR, C
NOËL, H
MALGHEM, J
MALDAGUE, B. E
VANDE BERG, B. C
description Two cases of treated plasma cell lesions of bone are reported for which contrast-enhanced MRI had suggested necrosis, based on lack of enhancement after gadolinium injection, and in which pathologic examinations revealed the presence of extensive viable neoplastic tissue. These cases highlight the need for cautious interpretation of contrast-enhanced MRI signs of response to treatment and inactivity of lesions in the setting of plasma cell neoplasms.
doi_str_mv 10.1007/s002560050461
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subjects Adult
Biological and medical sciences
Bone and Bones - pathology
Bone Neoplasms - drug therapy
Bone Neoplasms - pathology
Bone Neoplasms - radiotherapy
Cell Survival
Contrast Media
Diseases of the osteoarticular system
Female
Gadolinium
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Middle Aged
Multiple Myeloma - drug therapy
Multiple Myeloma - pathology
Necrosis
NMR
Nuclear magnetic resonance
Plasma
Plasma Cells - pathology
Plasmacytoma - pathology
Plasmacytoma - radiotherapy
Tumors of striated muscle and skeleton
title Treated plasma cell lesions of bone with MRI signs of response to treatment : unexpected pathological findings
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