Effect of anticancer drugs on production of transforming growth factor and expression of p53 AND Bcl-2 proteins by MCF-7 and T47D cell lines of human breast carcinoma

To compare the capability of methotrexate, cisplatin, doxorubicine and vincristine to induce production of the transforming growth factor beta(1) (TGF-beta(1)) in two cell lines - MCF-7 and T47D - of human breast carcinoma, as well as to study sensitivity of these cells to TGF-beta(1) and mentioned...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Experimental oncology 2008-03, Vol.30 (1), p.35-41
Hauptverfasser:	Stoika, R S, Yakymovych, I A, Kashchak, N I, Boyko, M M, Korynevska, A V, Klyuchyvska, O Yu, Shafranska, G I, Yakymovych, M Ya, Zhylchuk, V Ye, Kudryavets, Yu Y, Vorontsova, A L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - pharmacology Breast Neoplasms - metabolism Carcinoma - metabolism Cell Line, Tumor Cell Proliferation - drug effects Cell Survival - drug effects Cisplatin - pharmacology Doxorubicin - pharmacology Humans Jurkat Cells Methotrexate - pharmacology Mice Proto-Oncogene Proteins c-bcl-2 - metabolism Transforming Growth Factor beta1 - metabolism Transforming Growth Factor beta1 - pharmacology Tumor Suppressor Protein p53 - metabolism Vincristine - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!