Temporal change in N-acetyl-aspartate concentrations in adolescents with bipolar depression treated with lithium

This proton magnetic resonance spectroscopy (1H MRS) study identified the in vivo effects of lithium on N-acetyl-aspartate (NAA) concentrations in adolescent bipolar depression. Twenty eight adolescents with bipolar I disorder in a depressive episode received open-label lithium 30 mg/kg, adjusted to...

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Veröffentlicht in:	Journal of child and adolescent psychopharmacology 2008-04, Vol.18 (2), p.132-139
Hauptverfasser:	Patel, Nick C, DelBello, Melissa P, Cecil, Kim M, Stanford, Kevin E, Adler, Caleb M, Strakowski, Stephen M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Affect - drug effects Affect - physiology Amino acids Antimanic Agents - therapeutic use Aspartate Aspartic Acid - analogs & derivatives Aspartic Acid - metabolism Bipolar disorder Bipolar Disorder - blood Bipolar Disorder - drug therapy Bipolar Disorder - psychology Brain Child Child psychology Diagnosis Dominance, Cerebral - physiology Dosage and administration Drug therapy Female Follow-Up Studies Humans Image Processing, Computer-Assisted Lithium Lithium Compounds - pharmacokinetics Lithium Compounds - therapeutic use Magnetic Resonance Spectroscopy Male Mental depression Physiological aspects Prefrontal Cortex - drug effects Prefrontal Cortex - physiopathology Psychopathology Software Teenagers
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