Distinct cytochrome P450 aromatase isoforms in the common carp ( Cyprinus carpio ): Sexual dimorphism and onset of ontogenic expression

Abstract Cytochrome P450 aromatase (CYP19) is a key enzyme in the steroidogenic pathway that catalyses the conversion of testosterone to estrogen, and therefore is thought to influence gonadal sex differentiation. In an effort to understand the role of this enzyme in ovarian differentiation, we isol...

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Veröffentlicht in:	General and comparative endocrinology 2008-05, Vol.156 (3), p.499-508
Hauptverfasser:	Barney, Megan L, Patil, Jawahar G, Gunasekera, Rasanthi M, Carter, Chris G
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Aging - physiology Animals Aromatase - genetics Brain Brain - enzymology Carps - physiology Cyprinus carpio Data Interpretation, Statistical DNA Primers DNA, Complementary - biosynthesis DNA, Complementary - genetics Endocrinology & Metabolism Estrogenic pathway Female Freshwater Gene Expression Regulation, Enzymologic - genetics Gene Expression Regulation, Enzymologic - physiology Gonad Isoenzymes - genetics Larva - metabolism Male Ovary - enzymology Quantitative real-time PCR Reproduction Reverse Transcriptase Polymerase Chain Reaction Sex Characteristics Sex differentiation Teleostei Temperature Zygote - metabolism
Online-Zugang:	Volltext
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