Noninvasive In Vivo Delivery of Transgene via Adeno-Associated Virus into Supporting Cells of the Neonatal Mouse Cochlea

There are a number of genetic diseases that affect the cochlea early in life, which require normal gene transfer in the early developmental stage to prevent deafness. The delivery of adenovirus (AdV) and adeno-associated virus (AAV) was investigated to elucidate the efficiency and cellular specifici...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Human gene therapy 2008-04, Vol.19 (4), p.384-390
Hauptverfasser:	IIZUKA, Takashi, KANZAKI, Sho, MOCHIZUKI, Hideki, INOSHITA, Ayako, NARUI, Yuya, FURUKAWA, Masayuki, KUSUNOKI, Takeshi, SAJI, Makoto, OGAWA, Kaoru, IKEDA, Katsuhisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviruses Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Animals, Newborn Applied cell therapy and gene therapy Biological and medical sciences Biotechnology Care and treatment Cochlea - cytology Cochlea - metabolism Cochlea - virology Deafness Dependovirus - genetics Evoked Potentials, Auditory, Brain Stem Female Fundamental and applied biological sciences. Psychology Gene therapy Genetic aspects Genetic transformation Genetic Vectors - administration & dosage Genetic Vectors - genetics Health. Pharmaceutical industry Industrial applications and implications. Economical aspects Male Medical sciences Methods Mice Mice, Inbred C57BL Risk factors Transduction, Genetic Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transgenes - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!