Terminal end bud maintenance in mammary gland is dependent upon FGFR2b signaling

We previously demonstrated that Fibroblast Growth Factor 10 (FGF10) and its receptor FGFR2b play a key role in controlling the very early stages of mammary gland development during embryogenesis [Mailleux, A.A., Spencer-Dene, B., Dillon, C., Ndiaye, D., Savona-Baron, C., Itoh, N., Kato, S., Dickson,...

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Veröffentlicht in:	Developmental biology 2008-05, Vol.317 (1), p.121-131
Hauptverfasser:	Parsa, Sara, Ramasamy, Suresh K., De Langhe, Stijn, Gupte, Varsha V., Haigh, Jody J., Medina, Daniel, Bellusci, Savério
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Branching Cell Proliferation Cell Survival Ductal epithelium Epithelial Cells - cytology Female Fgf10 Fgfr2b Fibroblast Growth Factor 10 - metabolism Mammary Glands, Animal - cytology Mammary Glands, Animal - growth & development Mammary Glands, Animal - metabolism Mice Post-natal mammary gland development Proliferation Receptor, Fibroblast Growth Factor, Type 1 - metabolism Receptor, Fibroblast Growth Factor, Type 2 - metabolism Signal Transduction Stem Cells - cytology Terminal end buds
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