In- situ detection of drugs-of-abuse on clothing using confocal Raman microscopy
This study describes the application of confocal Raman microscopy to the detection and identification of drugs-of-abuse in situ on undyed natural synthetic fibres, and coloured textile specimens. Raman spectra were obtained from drug particles trapped between the fibres of the specimens. Pure sample...
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| Veröffentlicht in: | Analytica chimica acta 2008-05, Vol.615 (1), p.63-72 |
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| creator | Ali, Esam M.A. Edwards, Howell G.M. Hargreaves, Michael D. Scowen, Ian J. |
| description | This study describes the application of confocal Raman microscopy to the detection and identification of drugs-of-abuse
in situ on undyed natural synthetic fibres, and coloured textile specimens. Raman spectra were obtained from drug particles trapped between the fibres of the specimens. Pure samples of cocaine hydrochloride and
N-methyl-3,4-methylenedioxy-amphetamine HCl (MDMA-HCl) were used in this study. Raman spectra were collected from drug particles of an average size in the range 5–15
μm. Despite the presence of spectral bands arising from the natural and synthetic polymer and dyed textiles, the drugs could be identified by their characteristic Raman bands. If necessary, interfering bands could be successfully removed by spectral subtraction. Furthermore, Raman spectra were recorded from drug particles trapped between the fibres of highly fluorescent specimens. Interference from the fibres, including background fluorescence, was overcome by careful focusing of the confocal beam and the resulting spectra allow ready differentiation from interference from the fibres substrate bands. Spectra of several drugs-of-abuse on dyed and undyed clothing substrates were readily obtained within 3
min with little or no sample preparation and with no alteration of the evidential material. |
| doi_str_mv | 10.1016/j.aca.2008.03.051 |
| format | Article |
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in situ on undyed natural synthetic fibres, and coloured textile specimens. Raman spectra were obtained from drug particles trapped between the fibres of the specimens. Pure samples of cocaine hydrochloride and
N-methyl-3,4-methylenedioxy-amphetamine HCl (MDMA-HCl) were used in this study. Raman spectra were collected from drug particles of an average size in the range 5–15
μm. Despite the presence of spectral bands arising from the natural and synthetic polymer and dyed textiles, the drugs could be identified by their characteristic Raman bands. If necessary, interfering bands could be successfully removed by spectral subtraction. Furthermore, Raman spectra were recorded from drug particles trapped between the fibres of highly fluorescent specimens. Interference from the fibres, including background fluorescence, was overcome by careful focusing of the confocal beam and the resulting spectra allow ready differentiation from interference from the fibres substrate bands. Spectra of several drugs-of-abuse on dyed and undyed clothing substrates were readily obtained within 3
min with little or no sample preparation and with no alteration of the evidential material.</description><identifier>ISSN: 0003-2670</identifier><identifier>EISSN: 1873-4324</identifier><identifier>DOI: 10.1016/j.aca.2008.03.051</identifier><identifier>PMID: 18440364</identifier><identifier>CODEN: ACACAM</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Analytical chemistry ; Animals ; Chemistry ; Cocaine - analysis ; Cocaine hydrochloride ; Coloring Agents - chemistry ; Confocal Raman microscopy ; Cotton Fiber ; Drug discrimination ; Exact sciences and technology ; Fluorescence ; Forensic ; Forensic Sciences - methods ; N-methyl-3,4-methylenedioxy-amphetamine hydrochloride ; N-Methyl-3,4-methylenedioxyamphetamine - analysis ; Particle Size ; Polyesters - chemistry ; Silk - chemistry ; Spectrometric and optical methods ; Spectrum Analysis, Raman - methods ; Textiles ; Wool - chemistry</subject><ispartof>Analytica chimica acta, 2008-05, Vol.615 (1), p.63-72</ispartof><rights>2008 Elsevier B.V.</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c412t-47a449e9ef91f1f7e14def79bf765c3a097bba7e13170a05db10804b8def57523</citedby><cites>FETCH-LOGICAL-c412t-47a449e9ef91f1f7e14def79bf765c3a097bba7e13170a05db10804b8def57523</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0003267008005643$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20310942$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18440364$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ali, Esam M.A.</creatorcontrib><creatorcontrib>Edwards, Howell G.M.</creatorcontrib><creatorcontrib>Hargreaves, Michael D.</creatorcontrib><creatorcontrib>Scowen, Ian J.</creatorcontrib><title>In- situ detection of drugs-of-abuse on clothing using confocal Raman microscopy</title><title>Analytica chimica acta</title><addtitle>Anal Chim Acta</addtitle><description>This study describes the application of confocal Raman microscopy to the detection and identification of drugs-of-abuse
in situ on undyed natural synthetic fibres, and coloured textile specimens. Raman spectra were obtained from drug particles trapped between the fibres of the specimens. Pure samples of cocaine hydrochloride and
N-methyl-3,4-methylenedioxy-amphetamine HCl (MDMA-HCl) were used in this study. Raman spectra were collected from drug particles of an average size in the range 5–15
μm. Despite the presence of spectral bands arising from the natural and synthetic polymer and dyed textiles, the drugs could be identified by their characteristic Raman bands. If necessary, interfering bands could be successfully removed by spectral subtraction. Furthermore, Raman spectra were recorded from drug particles trapped between the fibres of highly fluorescent specimens. Interference from the fibres, including background fluorescence, was overcome by careful focusing of the confocal beam and the resulting spectra allow ready differentiation from interference from the fibres substrate bands. Spectra of several drugs-of-abuse on dyed and undyed clothing substrates were readily obtained within 3
min with little or no sample preparation and with no alteration of the evidential material.</description><subject>Analytical chemistry</subject><subject>Animals</subject><subject>Chemistry</subject><subject>Cocaine - analysis</subject><subject>Cocaine hydrochloride</subject><subject>Coloring Agents - chemistry</subject><subject>Confocal Raman microscopy</subject><subject>Cotton Fiber</subject><subject>Drug discrimination</subject><subject>Exact sciences and technology</subject><subject>Fluorescence</subject><subject>Forensic</subject><subject>Forensic Sciences - methods</subject><subject>N-methyl-3,4-methylenedioxy-amphetamine hydrochloride</subject><subject>N-Methyl-3,4-methylenedioxyamphetamine - analysis</subject><subject>Particle Size</subject><subject>Polyesters - chemistry</subject><subject>Silk - chemistry</subject><subject>Spectrometric and optical methods</subject><subject>Spectrum Analysis, Raman - methods</subject><subject>Textiles</subject><subject>Wool - chemistry</subject><issn>0003-2670</issn><issn>1873-4324</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1r3DAQQEVpaTZpf0AvxZf2ZmfGki2bnEJoPiCQEtqzkOVRqsW2NpIdyL-PzC7NLblo0PBmmHnD2DeEAgHr022hjS5KgKYAXkCFH9gGG8lzwUvxkW0AgOdlLeGIHce4Td8SQXxmR9gIAbwWG_b7Zsqz6OYl62kmMzs_Zd5mfVgeYu5trrslUpaSZvDzPzc9ZEtcX-Mn640esns96ikbnQk-Gr97_sI-WT1E-nqIJ-zv5a8_F9f57d3VzcX5bW4ElnMupBaipZZsixatJBQ9Wdl2VtaV4Rpa2XU6pTlK0FD1HUIDomsSVcmq5Cfs577vLvjHheKsRhcNDYOeyC9R1S0mC1i9C3IOdS1lk0Dcg-sqMZBVu-BGHZ4Vglp9q61KvtXqWwFXyXeq-X5ovnQj9a8VB8EJ-HEAdEy6bNCTcfE_VwJHaMW6ztmeo-TsyVFQ0TiaDPUupLOo3rs3xngB-6Ocgw</recordid><startdate>20080512</startdate><enddate>20080512</enddate><creator>Ali, Esam M.A.</creator><creator>Edwards, Howell G.M.</creator><creator>Hargreaves, Michael D.</creator><creator>Scowen, Ian J.</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TB</scope><scope>7U5</scope><scope>8FD</scope><scope>FR3</scope><scope>KR7</scope><scope>L7M</scope><scope>7X8</scope></search><sort><creationdate>20080512</creationdate><title>In- situ detection of drugs-of-abuse on clothing using confocal Raman microscopy</title><author>Ali, Esam M.A. ; Edwards, Howell G.M. ; Hargreaves, Michael D. ; Scowen, Ian J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c412t-47a449e9ef91f1f7e14def79bf765c3a097bba7e13170a05db10804b8def57523</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Analytical chemistry</topic><topic>Animals</topic><topic>Chemistry</topic><topic>Cocaine - analysis</topic><topic>Cocaine hydrochloride</topic><topic>Coloring Agents - chemistry</topic><topic>Confocal Raman microscopy</topic><topic>Cotton Fiber</topic><topic>Drug discrimination</topic><topic>Exact sciences and technology</topic><topic>Fluorescence</topic><topic>Forensic</topic><topic>Forensic Sciences - methods</topic><topic>N-methyl-3,4-methylenedioxy-amphetamine hydrochloride</topic><topic>N-Methyl-3,4-methylenedioxyamphetamine - analysis</topic><topic>Particle Size</topic><topic>Polyesters - chemistry</topic><topic>Silk - chemistry</topic><topic>Spectrometric and optical methods</topic><topic>Spectrum Analysis, Raman - methods</topic><topic>Textiles</topic><topic>Wool - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ali, Esam M.A.</creatorcontrib><creatorcontrib>Edwards, Howell G.M.</creatorcontrib><creatorcontrib>Hargreaves, Michael D.</creatorcontrib><creatorcontrib>Scowen, Ian J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>Analytica chimica acta</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ali, Esam M.A.</au><au>Edwards, Howell G.M.</au><au>Hargreaves, Michael D.</au><au>Scowen, Ian J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In- situ detection of drugs-of-abuse on clothing using confocal Raman microscopy</atitle><jtitle>Analytica chimica acta</jtitle><addtitle>Anal Chim Acta</addtitle><date>2008-05-12</date><risdate>2008</risdate><volume>615</volume><issue>1</issue><spage>63</spage><epage>72</epage><pages>63-72</pages><issn>0003-2670</issn><eissn>1873-4324</eissn><coden>ACACAM</coden><abstract>This study describes the application of confocal Raman microscopy to the detection and identification of drugs-of-abuse
in situ on undyed natural synthetic fibres, and coloured textile specimens. Raman spectra were obtained from drug particles trapped between the fibres of the specimens. Pure samples of cocaine hydrochloride and
N-methyl-3,4-methylenedioxy-amphetamine HCl (MDMA-HCl) were used in this study. Raman spectra were collected from drug particles of an average size in the range 5–15
μm. Despite the presence of spectral bands arising from the natural and synthetic polymer and dyed textiles, the drugs could be identified by their characteristic Raman bands. If necessary, interfering bands could be successfully removed by spectral subtraction. Furthermore, Raman spectra were recorded from drug particles trapped between the fibres of highly fluorescent specimens. Interference from the fibres, including background fluorescence, was overcome by careful focusing of the confocal beam and the resulting spectra allow ready differentiation from interference from the fibres substrate bands. Spectra of several drugs-of-abuse on dyed and undyed clothing substrates were readily obtained within 3
min with little or no sample preparation and with no alteration of the evidential material.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><pmid>18440364</pmid><doi>10.1016/j.aca.2008.03.051</doi><tpages>10</tpages></addata></record> |
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| subjects | Analytical chemistry Animals Chemistry Cocaine - analysis Cocaine hydrochloride Coloring Agents - chemistry Confocal Raman microscopy Cotton Fiber Drug discrimination Exact sciences and technology Fluorescence Forensic Forensic Sciences - methods N-methyl-3,4-methylenedioxy-amphetamine hydrochloride N-Methyl-3,4-methylenedioxyamphetamine - analysis Particle Size Polyesters - chemistry Silk - chemistry Spectrometric and optical methods Spectrum Analysis, Raman - methods Textiles Wool - chemistry |
| title | In- situ detection of drugs-of-abuse on clothing using confocal Raman microscopy |
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