A common pathway for regulation of nutritive blood flow to the brain: arterial muscle membrane potential and cytochrome P450 metabolites

ABSTRACT Perfusion pressure to the brain must remain relatively constant to provide rapid and efficient distribution of blood to metabolically active neurones. Both of these processes are regulated by the level of activation and tone of cerebral arterioles. The active state of cerebral arterial musc...

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Veröffentlicht in:	Acta physiologica Scandinavica 1998-12, Vol.164 (4), p.527-532
Hauptverfasser:	HARDER, D.R., ROMAN, R.J., GEBREMEDHIN, D., BIRKS, E.K., LANGE, A.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals astrocytes Biological and medical sciences Brain Chemistry - physiology Cerebral Arteries - cytology Cerebral Arteries - enzymology Cerebral Arteries - physiology Cerebrovascular Circulation - physiology Cytochrome P-450 Enzyme System - metabolism cytochrome P450 enzymes functional hyperaemia Fundamental and applied biological sciences. Psychology Hemodynamics. Rheology Homeostasis Humans K+ channel activity membrane potential Membrane Potentials - physiology Muscle, Smooth, Vascular - cytology Muscle, Smooth, Vascular - enzymology Muscle, Smooth, Vascular - physiology Vertebrates: cardiovascular system
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