Controversies in the Treatment of Wet Age-related Macular Degeneration

[...]Genentech has modified the molecule of bevacizumab without affecting the basis of its efficacy and now specifically addressed to treating this pathology. [...]ranibizumab was developed, it is forty times more expensive, although no indirect comparisons have proved significant differences betwee...

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Veröffentlicht in:American journal of ophthalmology 2008-05, Vol.145 (5), p.937-937
Hauptverfasser: Flores Moreno, Sandra, Bautista Paloma, Javier
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container_title American journal of ophthalmology
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creator Flores Moreno, Sandra
Bautista Paloma, Javier
description [...]Genentech has modified the molecule of bevacizumab without affecting the basis of its efficacy and now specifically addressed to treating this pathology. [...]ranibizumab was developed, it is forty times more expensive, although no indirect comparisons have proved significant differences between both treatments in efficacy.1-2 In this case, countries such as Italy, Germany, Austria, Finland, and New Zealand, is formally recommended to use bevacizumab instead of ranibizumab in AMD, while waiting for a head-to-head trial, which had to be promoted by independent organizations.
doi_str_mv 10.1016/j.ajo.2008.02.021
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subjects Angiogenesis Inhibitors - administration & dosage
Angiogenesis Inhibitors - adverse effects
Antibodies, Monoclonal - administration & dosage
Antibodies, Monoclonal - adverse effects
Antibodies, Monoclonal, Humanized
Bevacizumab
Choroidal Neovascularization - drug therapy
Choroidal Neovascularization - etiology
Clinical trials
Fluorescein Angiography
Humans
Injections
Macular degeneration
Macular Degeneration - complications
Macular Degeneration - drug therapy
Ophthalmology
Pharmaceutical industry
Treatment Outcome
Vascular Endothelial Growth Factor A - antagonists & inhibitors
Visual Acuity
Vitreous Body
title Controversies in the Treatment of Wet Age-related Macular Degeneration
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