High prevalence of low bone mass in thalassaemia major

Cooley's original description of β‐thalassaemia major included marked bone deformities as a characteristic feature. These were thought to be due to expansion of haemopoiesis attempting to compensate for the congenital anaemia. Regular blood transfusions from infancy prevents these skeletal prob...

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Veröffentlicht in:	British journal of haematology 1998-12, Vol.103 (4), p.911-915
Hauptverfasser:	JENSEN, C. E, TUCK, S. M, AGNEW, J. E, KONERU, S, MORRIS, R. W, YARDUMIAN, A, PRESCOTT, E, HOFFBRAND, A. V, WONKE, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anemias. Hemoglobinopathies beta-Thalassemia - complications beta-Thalassemia - physiopathology Biological and medical sciences Bone Density - physiology Bone Diseases, Metabolic - etiology bone mass bone mineral density Diseases of red blood cells Female Hematologic and hematopoietic diseases Hematology Humans Male Medical sciences osteopenia osteoporosis β thalassaemia
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