Chemical approaches to mapping the function of post-translational modifications
Strategies for the chemical construction of synthetic proteins with precisely positioned post-translational modifications or their mimics offer a powerful method for dissecting the complexity of functional protein alteration and the associated complexity of proteomes.
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| Veröffentlicht in: | The FEBS journal 2008-05, Vol.275 (9), p.1949-1959 |
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| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
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| container_end_page | 1959 |
|---|---|
| container_issue | 9 |
| container_start_page | 1949 |
| container_title | The FEBS journal |
| container_volume | 275 |
| creator | Gamblin, David P van Kasteren, Sander I Chalker, Justin M Davis, Benjamin G |
| description | Strategies for the chemical construction of synthetic proteins with precisely positioned post-translational modifications or their mimics offer a powerful method for dissecting the complexity of functional protein alteration and the associated complexity of proteomes. |
| doi_str_mv | 10.1111/j.1742-4658.2008.06347.x |
| format | Article |
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| ispartof | The FEBS journal, 2008-05, Vol.275 (9), p.1949-1959 |
| issn | 1742-464X 1742-4658 |
| language | eng |
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| source | Wiley Free Content; MEDLINE; IngentaConnect Free/Open Access Journals; Wiley Online Library Journals Frontfile Complete; Free Full-Text Journals in Chemistry |
| subjects | Animals Biochemistry Biotechnology chemoselective ligation Forecasting Glycoproteins - biosynthesis Glycosylation Humans Models, Molecular Molecular Mimicry post‐translational modification protein glycosylation Protein Interaction Mapping protein modification Protein Processing, Post-Translational Protein synthesis Proteomics synthetic proteins |
| title | Chemical approaches to mapping the function of post-translational modifications |
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