The effect of mitomycin-C on the biodistribution of 99Tcm-MDP in Balb/c mice

SUMMARYDrug therapy can alter the biodistribuition of radiopharmaceuticals. We studied the effect of mitomycin-C, a drug used in oncology, on the biodistribution in mice of Tc-methylene diphosphonic acid (Tc-MDP). Three doses of mitomycin-C were administered. After the last dose, Tc-MDP was injected...

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Veröffentlicht in:	Nuclear medicine communications 1998-12, Vol.19 (12), p.1177-1180
Hauptverfasser:	GOMES, M L, DE SOUZA BRAGA, A C, DE MATTOS, D M.M, SOUZA FREITAS, R DE, BOASQUEVISQUE, E M, BERNARDOFILHO, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Contrast media. Radiopharmaceuticals Dose-Response Relationship, Drug Female Medical sciences Mice Mice, Inbred BALB C Mitomycin - pharmacology Pharmacology. Drug treatments Radiopharmaceuticals - pharmacokinetics Technetium Tc 99m Medronate - pharmacokinetics Tissue Distribution - drug effects
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