Influence of killer immunoglobulin-like receptor HLA ligand matching on achievement of T-cell complete donor chimerism in related donor nonmyeloablative allogeneic hematopoietic stem cell transplantation

Achievement of complete donor chimerism (CDC) after allogeneic nonmyeloablative hematopoietic stem cell transplantation (NMHSCT) is important for preventing graft rejection and for generating a graft-vs-malignancy effect. The alloreactivity of NK cells and some T-cell subsets is mediated through the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2008-04, Vol.41 (8), p.709-714
Hauptverfasser:	Sobecks, R M, Ball, E J, Askar, M, Theil, K S, Rybicki, L A, Thomas, D, Brown, S, Kalaycio, M, Andresen, S, Pohlman, B, Dean, R, Sweetenham, J, Macklis, R, Bernhard, L, Cherni, K, Copelan, E, Maciejewski, J P, Bolwell, B J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bone marrow Bone marrow, stem cells transplantation. Graft versus host reaction Cell Biology Cell receptors Chimerism Cohort Studies Effector cells Female Fludarabine Genotype Genotypes Graft rejection Graft Rejection - genetics Graft Rejection - immunology Graft-versus-host reaction Grafting Health aspects Hematology Hematopoietic Stem Cell Transplantation - methods Hematopoietic stem cells Histocompatibility antigen HLA Histocompatibility Testing Humans Immunoglobulin-like receptors Immunoglobulins Internal Medicine Kaplan-Meier Estimate Killer cell immunoglobulin-like receptors Ligands Lymphocytes T Male Malignancy Matching Medical sciences Medicine Medicine & Public Health Middle Aged Natural killer cells original-article Physiological aspects Public Health Receptors Receptors, KIR - genetics Receptors, KIR - immunology Rejection Stem cell transplantation Stem Cells T cells T-Lymphocytes - transplantation Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation Chimera - genetics Transplantation Chimera - immunology Transplantation Conditioning - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!